Results 11 to 20 of about 42,066 (191)

Thyroglobulin and thyroglobulin antibody: an updated clinical and laboratory expert consensus [PDF]

European Journal of Endocrinology, 2023
AbstractObjectiveThyroglobulin measurement is the cornerstone of modern management of differentiated thyroid cancer, with clinical decisions on treatment and follow-up based on the results of such measurements. However, numerous factors need to be considered regarding measurement with and interpretation of thyroglobulin assay results.DesignThe present ...
Luca Giovanella, Federica D’Aurizio, Alicia Algeciras-Schimnich, Rainer Görges, Petra Petranovic Ovcaricek, R Michael Tuttle, W Edward Visser, Frederik A Verburg, Martyna Borowczyk, Luca Chiovato, Leonidas Duntas, Thyroid Section, Ulla Feldt-Rasmussen, Luisa Knappe, Laurence Leenhardt, Flavia Magri, Harald Rimmele, Ettore Seregni   +17 more
openaire   +3 more sources

Phylogenetic analysis of the human thyroglobulin regions [PDF]

Thyroid Research, 2012
Thyroglobulin is a large protein present in all vertebrates. It is synthesized in the thyrocytes and exported to lumen of the thyroid follicle, where its tyrosine residues are iodinated .
Belkadi Abdelaziz, Jacques Caroline, Savagner Frédérique, Malthièry Yves   +3 more
doaj   +3 more sources

Thyroglobulin Gene Mutation with Cold Nodule on Thyroid Scintigraphy [PDF]

Case Reports in Endocrinology, 2012
Thyroglobulin gene mutation is a rare cause of congenital hypothyroidism, but thyroglobulin gene mutations are thought to be associated with thyroid cancer development.
Toshio Kahara, Noboru Igarashi, Akira Hishinuma, Yuko Nakanishi, Akio Uchiyama, Atsuo Miwa, Shin Ishizawa, Yutaka Yamamoto, Hirofumi Noto, Hisashi Sumiya, Kazuhide Ishikura, Rika Usuda, Hiroyuki Iida   +12 more
doaj   +2 more sources

Thyroglobulin and Thyroglobulin Antibodies

, 2018
Differentiated thyroid cancer (DTC) is the most common endocrine cancer, and its incidence has increased in recent decades. Initial treatment usually consists of total thyroidectomy followed by ablation of thyroid remnants by iodine-131 depending on post-operative risk stratification. As thyroid cells are assumed to be the only source of thyroglobulin (
Giovanella L., D'Aurizio F., Tozzoli R., Schalin-Jantti C., Feldt-Rasmussen U.   +4 more
openaire   +3 more sources

Proteomic and Postproteomic Characterization of Keratan Sulfate-Glycanated Isoforms of Thyroglobulin and Transferrin Uniquely Elaborated by Papillary Thyroid Carcinomas. [PDF]

, 2003
Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance.
Goletz, Steffen, Colombatti, Alfonso, Bisceglia, Michele, Perissinotto, Daniela, Magro, Gaetano, Brown, Gavin, Grasso, Sebastiano, Müller, Eva-Christina, Ellis, Timothy, Otto, Albrecht, Perris, Roberto, Schiappacassi, Monica   +11 more
core   +5 more sources

Preablative stimulated Thyroglobulin (sTg) versus sTg/TSH ratio in prediction of ablation outcome in patients with papillary thyroid cancer [PDF]

Egyptian Journal of Nuclear Medicine, 2023
Introduction: Many factors can affect ablation outcome in patients with papillary thyroid cancer. One of the good predictors is stimulated Tg (sTg). Since it is influenced by many factors including serum TSH level, it was postulated that sTg /TSH can be ...
Maha Salama, Sherin Wagieh, Mirna Tarek, Nahla El-Sayed   +3 more
doaj   +1 more source

Effect of thyroglobulin level before ablative Radioactive Iodine on response and survival among patients with Differentiated Thyroid Carcinoma [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2023
Objective: A retrospective study to assess the relationship between stimulated Tg (sTg) levels before RAI therapy and response to RAI in patients with DTC who underwent thyroidectomy. Also, to evaluate sTg before RAI impact on DFS (disease-free survival).
Ahmad Abdelrahman
doaj   +1 more source

The subunits of thyroglobulin [PDF]

Biochemical Journal, 1970
1. Pig thyroglobulin was reduced with dithiothreitol in the presence of sodium dodecyl sulphate, 8m-urea or 6m-guanidinium chloride. 2. The molecular weights of the reduction products were about 165000. 3. Two stable subunits with molecular weights as low as 35000 and 20000 were separated by Sephadex chromatography after prolonged exposure of the ...
P A, Charlwood, R, Pitt-Rivers, H L, Schwartz   +2 more
openaire   +2 more sources

A Novel Mutation in the Thyroglobulin Gene Resulting in Neonatal Goiter and Congenital Hypothyroidism in an Eritrean Infant

JCRPE, 2022
Congenital hypothyroidism (CH) due to dyshormonogenesis may occur due to mutations in any of the key genes involved in thyroid hormone biosynthesis (TG, TPO, DUOX2, DUOXA2, SLC5A5, IYD, SLC26A4 and SLC26A7).
Eve Stern, Nadia Schoenmakers, Adeline K. Nicholas, Eran Kassif, Orit Pinhas Hamiel, Yonatan Yeshayahu   +5 more
doaj   +1 more source

Effect of therapeutic radioiodine activity on ablation response in differentiated thyroid cancer patients with cut-off serum thyroglobulin levels after 2 weeks of thyroid hormone withdrawal: a retrospective study [PDF]

Journal of Medicine and Life Science, 2022
This retrospective study aimed to investigate whether there was a difference in the success rate of removal of residual thyroid tissue in patients with the same cutoff serum thyroglobulin (Tg) value―measured 2 weeks after thyroid hormone withdrawal (THW)―
Ji Young Lee, Hee-Sung Song, Young Hwan Kim   +2 more
doaj   +1 more source