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Test Utilization for Thyroglobulin and Anti-Thyroglobulin Antibody Assays in Korea
Clinical Laboratory, 2021When measuring thyroglobulin (Tg), simultaneous measurement of Tg autoantibodies (Ab) is recommended by clinical guidelines for follow-up of patients with differentiated thyroid cancers after thyroidectomy and radioactive iodine ablation. We aimed to investigate test utilization of Tg and Tg Ab assays in local clinics and hospitals in Korea.We ...
Sang Gon Lee +3 more
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Thyroglobulin and anti-thyroglobulin assays in thyroid cancer monitoring
Clinical Biochemistry, 2009To compare four methods for thyroglobulin (Tg) quantitation and three methods for detection and quantitation of thyroglobulin antibodies (Tg-Ab). We also wanted to explore the premise that thyroglobulin antibodies, as determined by commercially available assays, interfere with thyroglobulin assays in a predictable way.Split sample method comparisons ...
Tom Dembinski, John Krahn
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Assay of thyroglobulin in serum with thyroglobulin autoantibodies: an unobtainable goal?
The Journal of Clinical Endocrinology & Metabolism, 1995Measurement of thyroglobulin (Tg) in serum with anti-Tg autoantibodies (TgAb) represents a difficult challenge. Immunoradiometric assays (IRMA) employing monoclonal anti-Tg antibodies not cross-reacting with endogenous TgAb have recently been developed and proposed for Tg assays in TgAb-positive sera.
MARIOTTI S. +7 more
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Thyroglobulin in struma ovarii
Journal of Surgical Research, 1978Abstract The serum assay of thyroglobulin offers a means of detection of recurrent thyroid cancer. We present immunohistochemical studies suggesting that the presence of ovarian thyroid tissue containing and producing thyroglobulin may introduce a source of diagnostic confusion.
Virginia A. LiVolsi +2 more
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Thyroglobulin: A Clinical Review
Endocrine Practice, 1995The introduction of the new assays for thyroglobulin (Tg) with a sensitivity of 1 to 3 mg/L has made it unnecessary to terminate thyroxine suppression therapy to determine Tg level. Thyroid-stimulating hormone should always be assessed in conjunction with the Tg to ensure that it is not high; as long as it is suppressed to normal, subnormal suppression
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Properties of carbohydrate-stripped thyroglobulin III. solubility characteristics of thyroglobulin
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1977In studying the solubility characteristics of thyroglobulin, it was found that the removal of sialic acid residues from either human or hog thyroglobulin by treatment with neuraminidase markedly decreased the solubility in salt solutions. On the other hand, naturally sialic acid-rich thyroglobulin obtained from human diffuse goiter was slightly more ...
Toshihiko Kondo +2 more
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Intraluminal Iodination of Thyroglobulin*
Endocrinology, 1984The intraluminal distribution of newly synthesized (injection of [3H]leucine) and newly iodinated (injection of Na125I) proteins in thyroids of rats given T4 for 2 days was studied with quantitative electron microscopic autoradiography. Three, 4.5, and 6 h after [3H]leucine about 90%, 85%, and 65%, respectively, of the luminal label was confined to the
Torsten Öfverholm, Lars E. Ericson
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Properties of thyroglobulin. XVIII. Isolation of thyroglobulin subunits
Biochemistry, 1969Harold Edelhoch +2 more
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