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Thyroid associated orbitopathy is a common manifestation of Graves’ disease. There are many options which can be considered for treatment of this condition.
Asok Kumar Saha +4 more
doaj
Biological effects of thyrotropin receptor activation on human orbital dreadipocytes [PDF]
purpose. Thyrotropin receptor (TSHR) expression is upregulated in the orbits of patients with Graves ophthalmopathy (GO), most of whom have TSHR-stimulating antibodies.
Baker, Glynn +5 more
core +1 more source
Association of polymorphism in genes encoding κB inhibitors (IκB) with susceptibility to and phenotype of Graves' disease: a case-control study [PDF]
Background Genes related to the nuclear factor-κB (NF-κB), a key transcription factor involved in regulation of immune responses, are interesting candidates for association studies in autoimmune disorders.
Alina Kurylowicz +4 more
core +2 more sources
Increased percentage of L-selectin+ and ICAM-1+ peripheral blood CD4+/CD8+ T cells in active Graves' ophthalmopathy. [PDF]
The purpose of the study was to evaluate the percentage of CD4+/CD8+ peripheral T cells expressing CD62L+ and CD54+ in patients with Graves' disease and to assess if these estimations could be helpful as markers of active ophthalmopathy.
A Bossowski +25 more
core +3 more sources
Update on the medical treatment of Graves’ ophthalmopathy
Gregory J Griepentrog, James A GarrityDepartment of Ophthalmology, Mayo Clinic, Rochester, MN, USAPurpose: To review recent advances in the understanding of Graves’ ophthalmopathy (GO) pathogenesis as well as discuss current and future medical ...
Gregory J Griepentrog, James A Garrity
doaj
El síndrome metabólico es un conjunto de factores de riesgo, que requieren la presencia de obesidad de predominio central, dislipemia, hipertensión arterial y resistencia a la insulina, todos ellos, predictores de enfermedad cardiovascular y diabetes ...
Güemes-Hidalgo, M., Muñoz-Calvo, M. T.
core +1 more source
Unexpected conversion from hypothyroidism to an euthyroid state due to Graves’ disease in a patient with an ectopic thyroid [PDF]
A 15-year-old woman was diagnosed with hypothyroidism and unilateral ectopic thyroid. Levothyroxine treatment was introduced; however, the patient was non-compliant and took the medication irregularly.
Aleksandra Hernik +2 more
core +1 more source
[Thyroid associated ophthalmopathy].
Thyroid associated ophthalmopathy is an uncommon disease, characterized by a diffuse inflammation of the orbit in a bilateral and asymmetric pattern, causing proptosis and swelling of the eyelids and conjuntiva. In 90% of the patients it is associated with Graves' disease, however it may occur with hipothyroidism or even without thyroid disease. During
José Luís, Metello +3 more
openaire +1 more source
Objective: To assess whether three-wall surgical orbital decompression confers any benefit over two-wall surgical orbital decompression in terms of decrease in proptosis and new-onset diplopia.
Haissan Iftikhar +5 more
doaj +1 more source
Tom McCorquodale,1 Hooshang Lahooti,1 Bamini Gopinath,2 Jack R Wall11Department of Medicine, Nepean Clinical School, the University of Sydney, Penrith, NSW, Australia; 2Centre for Vision Research, the University of Sydney, Westmead Hospital, Westmead ...
McCorquodale T +3 more
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