Results 111 to 120 of about 144,897 (340)

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

INSULIN RESISTANCE AND BODY MASS INDEX WITH REGARD TO VARIOUS THYROID STIMULATING HORMONE REFERENCE INTERVALS [PDF]

open access: green, 1969
Neval Aksoy   +5 more
openalex   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

open access: yesCancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae   +16 more
wiley   +1 more source

Effect of Hydroalcoholic Extract of Truffle (Terfezia Boudieri) on Serum Level of Thyroid Hormones in Male Rats

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2020
Background and Aim: Thyroid gland makes thyroxine (T4) and triiodothyronine (T3) hormones. These hormones are really effective in regulating and control of basal metabolism.
Eslam Zabihi   +3 more
doaj  

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Assessment of hormonal activity in patients with premature ejaculation

open access: yesInternational Brazilian Journal of Urology
Purpose Premature ejaculation is considered the most common type of male sexual dysfunction. Hormonal controls of ejaculation have not been exactly elucidated. The aim of our study is to investigate the role of hormonal factors in patients with premature
Lütfi Canat   +4 more
doaj   +1 more source

Amiodarone-induced thyroid dysfunction masking a resistance to thyroid hormone diagnosis in an Octogenarian with cardiac manifestations

open access: yesJournal of Clinical and Translational Endocrinology Case Reports, 2023
Background: Resistance to thyroid hormone (RTH) syndrome is a rare clinical condition and manifests biochemically as persistent hyperthyroxinemia with unsuppressed thyroid-stimulating hormone (TSH) levels.
Alamin Alkundi, Rabiu Momoh
doaj  

What are the causes of elevated TSH in a newborn? [PDF]

open access: yes, 2008
Congenital hypothyroidism is a critical cause of elevated thyroid-stimulating hormone (TSH) in newborns; evaluate all neonates with an elevated TSH for congenital hypothyroidism (strength of recommendation [SOR]: A).
Crotteau, Charles A.   +2 more
core  

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

open access: yesCancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu   +16 more
wiley   +1 more source

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