Results 111 to 120 of about 144,897 (340)
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
INSULIN RESISTANCE AND BODY MASS INDEX WITH REGARD TO VARIOUS THYROID STIMULATING HORMONE REFERENCE INTERVALS [PDF]
Neval Aksoy+5 more
openalex +1 more source
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae+16 more
wiley +1 more source
Background and Aim: Thyroid gland makes thyroxine (T4) and triiodothyronine (T3) hormones. These hormones are really effective in regulating and control of basal metabolism.
Eslam Zabihi+3 more
doaj
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source
Assessment of hormonal activity in patients with premature ejaculation
Purpose Premature ejaculation is considered the most common type of male sexual dysfunction. Hormonal controls of ejaculation have not been exactly elucidated. The aim of our study is to investigate the role of hormonal factors in patients with premature
Lütfi Canat+4 more
doaj +1 more source
Background: Resistance to thyroid hormone (RTH) syndrome is a rare clinical condition and manifests biochemically as persistent hyperthyroxinemia with unsuppressed thyroid-stimulating hormone (TSH) levels.
Alamin Alkundi, Rabiu Momoh
doaj
Further observations on the teratogenic action of the thyroid stimulating hormone [PDF]
Allan R. Beaudoin
openalex +1 more source
What are the causes of elevated TSH in a newborn? [PDF]
Congenital hypothyroidism is a critical cause of elevated thyroid-stimulating hormone (TSH) in newborns; evaluate all neonates with an elevated TSH for congenital hypothyroidism (strength of recommendation [SOR]: A).
Crotteau, Charles A.+2 more
core
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu+16 more
wiley +1 more source