Results 121 to 130 of about 157,181 (308)

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Association of iron status indicators with thyroid hormone concentrations during pregnancy: a systematic review and meta-analysis

open access: yesFrontiers in Endocrinology
BackgroundMaternal thyroid hormones play a vital role in fetal development, and imbalances can lead to adverse outcomes. Iron deficiency may impair thyroid function due to iron’s essential role in iodine oxidation during thyroid hormone synthesis.
Mohammadamin Parsaei   +6 more
doaj   +1 more source

What are the causes of elevated TSH in a newborn? [PDF]

open access: yes, 2008
Congenital hypothyroidism is a critical cause of elevated thyroid-stimulating hormone (TSH) in newborns; evaluate all neonates with an elevated TSH for congenital hypothyroidism (strength of recommendation [SOR]: A).
Crotteau, Charles A.   +2 more
core  

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma   +11 more
wiley   +1 more source

Pattern of Thyroid Profile in Elderly Persons

open access: yesGomal Journal of Medical Sciences, 2007
Background: Thyroid hormones, tri-iodothyronine and thyroxin are produced by thyroid gland and regulated by the hypothalamic-pituitary-thyroid axis. In old age this regulatory function may be altered.
Muhammad Shoaib Khan   +5 more
doaj  

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

open access: yesiLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang   +6 more
wiley   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

open access: yesiMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu   +6 more
wiley   +1 more source

CLINICAL PATHWAY OF PATIENTS WITH DIFFERENTIATED THYROID CANCER USING RECOMBINANT HUMAN THYROID-STIMULATING HORMONE

open access: yesКлінічна та профілактична медицина
Introduction. Differentiated thyroid cancer is a tumor with long-term survival, but requires long-term dynamic observation and radioactive iodine therapy. The key prereqisite for the effectiveness of radiotherapy and diagnostic monitoring is to achieve a
Rimma P. Tkachenko
doaj   +1 more source

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