Results 121 to 130 of about 406,228 (357)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource Limited Setting in Tanzania: A Case Report, Clinical Discussion and Brief Review of Existing Literature. [PDF]

, 2012
Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor ...
A Cénac, A Gutenberg, A Lecube, AH Zargar, C Ajith, D Castle, EH Sidibe, EM Tan, F Bakiri, Faheem G Sheriff, GK Leung, H Raff, HC Lee, J Honegger, JD Ji, JR Ouma, Kajiru G Kilonzo, ME Molitch, N Tubridy, P Caturegli, R Golden, R Goswami, RA Kristof, S Diederich, William P Howlett, Y Ozawa, Z Karaca, ZA Erkut   +27 more
core   +3 more sources

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

Cancer Communications, EarlyView.
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang, Yan Sun, Ao Deng, Jiahe Liu, Peijin Dai, Jing Chen, Chaoqun Deng, Hui Liu, Yuhang Hai, Yanran Tong, Yan‐e Du, Manran Liu, Haojun Luo   +12 more
wiley   +1 more source

Clinical and Laboratory Evaluation between Serum Cholesterol and Thyroid Stimulating Hormone Level in the Patients of Thyroid Dysfunction and Hypothyroidism

, 2021
Himani Pundir, Siddhartha Dan, Sunita Manhas   +2 more
openalex   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

What are the causes of elevated TSH in a newborn? [PDF]

, 2008
Congenital hypothyroidism is a critical cause of elevated thyroid-stimulating hormone (TSH) in newborns; evaluate all neonates with an elevated TSH for congenital hypothyroidism (strength of recommendation [SOR]: A).
Crotteau, Charles A., Kovach, Fran E., Rowland, Kathleen   +2 more
core  

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Assessment of hormonal activity in patients with premature ejaculation

International Brazilian Journal of Urology
Purpose Premature ejaculation is considered the most common type of male sexual dysfunction. Hormonal controls of ejaculation have not been exactly elucidated. The aim of our study is to investigate the role of hormonal factors in patients with premature
Lütfi Canat, Akif Erbin, Masum Canat, Mehmet Dinek, Turhan Çaşkurlu   +4 more
doaj   +1 more source

Maturation of the Secretion of Thyroid Hormone and Thyroid-Stimulating Hormone in the Fetus [PDF]

, 1991
J.G. Thorpe‐Beeston, K. H. Nicolaides, Carl V. Felton, Joan Butler, Alan M. McGregor   +4 more
openalex   +1 more source

Circulating Thyroxine, Thyroid-Stimulating Hormone, and Hypothyroid Status and the Risk of Prostate Cancer

PLoS ONE, 2012
Background Thyroid hormones may influence risk of cancer through their role in cell differentiation, growth, and metabolism. One study of circulating thyroid hormones supports this hypothesis with respect to prostate cancer.
A. Mondul, S. Weinstein, T. Bosworth, A. Remaley, J. Virtamo, D. Albanes   +5 more
semanticscholar   +1 more source