Results 31 to 40 of about 1,174,175 (255)

Role of Pax8 transcriptional factor in the differentiated thyroid [PDF]

, 2010
In Pax8-/- mice the thyroid anlage disappears around E11.5. At birth the gland appears as a rudimentary structure composed only of C cells while thyroid follicular cells are undetectable. Thus, this model does not allow the study of Pax8 function in the
Marotta, Pina
core   +1 more source

Efficacy of Selpercatinib in RET-Altered Thyroid Cancers

New England Journal of Medicine, 2020
BACKGROUND RET mutations occur in 70% of medullary thyroid cancers and RET fusions rarely in other thyroid cancers. We evaluated the efficacy and safety of selpercatinib, a selective RET inhibitor, in patients with advanced RET-altered thyroid cancers ...
Lori J. Wirth, E. Sherman, B. Robinson, B. Solomon, Hyunseok Kang, J. Lorch, F. Worden, M. Brose, J. Patel, S. Leboulleux, Y. Godbert, F. Barlesi, John C. Morris, T. Owonikoko, D. Tan, O. Gautschi, J. Weiss, C. de la Fouchardiére, M. Burkard, Janessa Laskin, M. Taylor, M. Kroiss, J. Medioni, J. Goldman, T. Bauer, B. Levy, Viola W. Zhu, N. Lakhani, V. Moreno, K. Ebata, M. Nguyen, Dana Heirich, E. Zhu, Xin Huang, Luxi Yang, J. Kherani, S. Rothenberg, A. Drilon, V. Subbiah, Manisha H. Shah, M. Cabanillas   +40 more
semanticscholar   +1 more source

Malignancy risk analysis in patients with inadequate fine needle aspiration cytology (FNAC) of the thyroid [PDF]

, 2012
Background Thyroid fine needle aspiration cytology (FNAC) is the standard diagnostic modality for thyroid nodules. However, it has limitations among which is the incidence of non-diagnostic results (Thy1).
Mehanna, Hisham M., Weickert, Martin O., Hisham Mehanna, Al Maqbali Talib, Tedla Miroslav, Weickert, Martin O, Talib Al Maqbali, Al Maqbali, Talib, Mehanna Hisham, Weickert Martin O., Martin O Weickert, Tedla, Miroslav, Mehanna, Hisham; id_orcid, Miroslav Tedla   +13 more
core   +1 more source

Thyroid-like function in the urochordate Ciona intestinalis [PDF]

, 2011
In the studies reported in the manuscript I investigated the involvement of Iodine and thyroxine (Thyroid Hormone, T4) in Ciona intestinalis metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown.
Staiano, Leopoldo
core   +1 more source

lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm

Mediators of Inflammation, 2023
As the most prevalent subtype of aortic aneurysm, abdominal aortic aneurysm (AAA) features the apoptosis, extracellular matrix (ECM) disruption, and inflammation response of vascular smooth muscle cells (VSMCs).
Ye Tian, Xinxi Li, Chao Bai, Zhenwei Yang, Lei Zhang, Jun Luo, Wenbin Zhang   +6 more
doaj   +1 more source

Duration of antithyroid drug treatment may predict weight gain after radioactive iodine therapy in patients with Graves’ disease

Heliyon, 2022
Background: Weight gain post-radioiodine (RAI) treatment is observed in patients with hyperthyroid Graves’ disease. Previous studies, mostly in Caucasian patients, demonstrated excessive weight gain averaging 5–7 kg from initial presentation.
Thewjitcharoen Yotsapon, Chatchomchuan Waralee, Prasatkaew Hussamon, Srichomchey Panita, Butadej Siriwan, Nakasatien Soontaree, Wanothayaroj Ekgaluck, Rajatanavin Rajata, Himathongkam Thep   +8 more
doaj   +1 more source

Thyroid Autoimmunity: Role of Anti-thyroid Antibodies in Thyroid and Extra-Thyroidal Diseases [PDF]

Frontiers in Immunology, 2017
Autoimmune diseases have a high prevalence in the population, and autoimmune thyroid disease (AITD) is one of the most common representatives. Thyroid autoantibodies are not only frequently detected in patients with AITD but also in subjects without manifest thyroid dysfunction.
Eleonore Fröhlich, Eleonore Fröhlich, Richard Wahl   +2 more
openaire   +3 more sources

Acoustic radiation force impulse imaging for differentiation of thyroid nodules [PDF]

, 2012
Background: Acoustic Radiation Force Impulse (ARFI)-imaging is an ultrasound-based elastography method enabling quantitative measurement of tissue stiffness.
Stefan Zeuzem, Lisa Voelkl (139194), Holzer, Katharina, Katharina Holzer (139190), Schroeter, Hartmut, Friedrich-Rust, Mireen, Dauth, Nina, Christian Berner, Katharina Holzer, Joerg Bojunga, Gesine Meyer (139188), Hartmut Schroeter (139199), Joerg Bojunga (139182), Berner, Christian, Meyer, Gesine, Lisa Voelkl, Herrmann, Eva, Nina Dauth (139184), Hartmut Schroeter, Voelkl, Lisa, Nina Dauth, Mireen Friedrich-Rust, Bojunga, Jörg, Eva Herrmann (139197), Gesine Meyer, Christian Berner (139186), Eva Herrmann, Mireen Friedrich-Rust (139200), Zeuzem, Stefan, Stefan Zeuzem (22856), Friedrich-Rust Mireen, Schroeter Hartmut, Dauth Nina, Herrmann Eva, Zeuzem Stefan, Voelkl Lisa, Holzer Katharina, Meyer Gesine, Bojunga Joerg, Berner Christian   +39 more
core   +2 more sources

Biological function of Cl 2 gene and it’s role in thyroid cancer [PDF]

, 2011
Here I report data to support a tumor suppressor role of the Cl 2 gene. Indeed, I detected a drastic reduction, of Cl 2 gene expression in almost all thyroid carcinomas analyzed, with respect to normal thyroid, with the lowest expression levels observed ...
Ferraro, Angelo
core   +1 more source

Impact of first-line treatment choice on long-term outcomes of hyperthyroid Graves’ disease patients with thyrotoxic periodic paralysis

Journal of Clinical & Translational Endocrinology, 2020
Background: Thyrotoxic periodic paralysis (TPP) is a unique manifestation of Graves’ disease. While it is uncommon in Asian, it is extremely rare in Caucasian patients (0.1–0.2%).
Krittadhee Karndumri, Yotsapon Thewjitcharoen, Waralee Chatchomchuan, Sriurai Porramatikul, Sirinate Krittiyawong, Ekgaluck Wanothayaroj, Siriwan Butadej, Soontaree Nakasatien, Rajata Rajatanavin, Thep Himathongkam   +9 more
doaj   +1 more source