Results 51 to 60 of about 954,700 (311)

Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass [PDF]

, 2011
Context: The hormonal factors involved in the regulation of peak bone mass (PBM) in men have not been fully investigated. Apart from gonadal steroids and somatotropic hormones, thyroid hormones are known to affect bone maturation and homeostasis and are ...
Fiers, Tom, Goemaere, Stefan, Kaufman, Jean, Lapauw, Bruno, ROEF, GREET, Taes, Youri, Zmierczak, Hans-Georg   +6 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Efficacy of Low-Kilovoltage X-Rays Intraoperative Radiation as Boost for Breast Cancer: A Systematic Review and Meta-Analysis

The Breast Journal, 2023
Background. Intraoperative radiotherapy (IORT) is a novel promising technology that may replace external beam radiation therapy (EBRT) as boost for patients receiving breast-conserving surgery.
Yuanjian Fan, Ruiwan Chen, Ying Lu, Ying Lin, Yunjian Zhang, Nan Shao, Shenming Wang, Dahong Nie, Zhen Shan   +8 more
doaj   +1 more source

CORRELATION OF FINE NEEDLE ASPIRATION AND FINAL HISTOPATHOLOGY IN THYROID DISEASE: A SERIES OF 702 PATIENTS MANAGED IN AN ENDOCRINE SURGICAL UNIT [PDF]

, 2012
Thyroid nodules are a common clinical entity found among the adult general population. With increasing use of imaging investigations like ultrasonography, there has been a significant rise in the detection of non-palpable thyroid nodules that require ...
Maharajan, Chandrasekaran, Rao, Himagirish   +1 more
core   +1 more source

Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level [PDF]

, 2013
Purpose: We designed our study to evaluate the hypothesis that gastric cancer is correlated with iodine deficiency or thyroid dysfunction. Materials and Methods: We investigated the total body iodine reserve, thyroid function status and autoimmune ...
Adabi, K., Haghpanah, V., Hatami, E., Heshmat, R., Jahangirrad, A., Keshtkar, A., Kia, A., Larijani, B., Nabizadeh, R., Rohani, D., Roshandel, G., Semnani, S., Tabaeizadeh, M.   +12 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Thyroid-hormone therapy and thyroid cancer: a reassessment. [PDF]

, 2005
Experimental studies and clinical data have demonstrated that thyroid-cell proliferation is dependent on thyroid-stimulating hormone (TSH), thereby providing the rationale for TSH suppression as a treatment for differentiated thyroid cancer.
BIONDI, BERNADETTE, Filetti S, Schlumberger M.   +2 more
core  

Thyroid Hemiagenesis Associated with Hashimoto’s Thyroiditis [PDF]

Case Reports in Endocrinology, 2013
Thyroid hemiagenesis is a rare congenital anomaly resulting from failure of one thyroid lobe development. We report a 23-year-old female presented with Hashimoto’s thyroiditis in left lobe, associated with hemiagenesis of right lobe and isthmus which was previously diagnosed as Graves’ hyperthyroidism, but developed further into Hashimoto’s thyroiditis
D. Nsame, A. Chadli, L. Hallab, S. El Aziz, H. El Ghomari, A. Farouqi   +5 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Risk stratification of neck lesions detected sonographically during the follow-up of differentiated thyroid cancer [PDF]

, 2016
Context: The European Thyroid Association (ETA) has classified post-treatment cervical ultrasound findings in thyroid cancer patients based on their association with disease persistence/recurrence.
BIFFONI, Marco, Costante, Giuseppe, DURANTE, COSIMO, FILETTI, SEBASTIANO, GIACOMELLI, Laura, GRANI, Giorgio, LAMARTINA, LIVIA, LUPO, STEFANIA, MARANGHI, MARIANNA, plasmati, katia, SPONZIELLO, Marialuisa, TRULLI, FABIANA, VERRIENTI, Antonella   +12 more
core   +1 more source