Results 81 to 90 of about 513,992 (266)

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian   +7 more
wiley   +1 more source

Theranostic Potentials of Metallic Nanoparticles in Thyroid Diseases: Challenges and Prospects

open access: yesInternational Journal of Nanomedicine
Siyu Li,1,* Ying Shi,2,* Xianbin Cheng,1 Mingmei Huangfu,1 Hao Zhang,1 Xiangfu Ding1 1Department of Thyroid Surgery, The Second Hospital of Jilin University, Changchun, 130000, People’s Republic of China; 2Department of Breast Surgery ...
Li S   +5 more
doaj  

EXPERIMENTAL THYROIDISM [PDF]

open access: yesJournal of Experimental Medicine, 1898
From the results of the various experiments already detailed I feel justified in drawing the following conclusions: (1) Absolutely fresh thyroid gland is not poisonous, in the usual sense of the term, when absorbed through the alimentary canal.
openaire   +2 more sources

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Significant role of 1,25-dihydroxyvitamin D on serum calcium levels after total thyroidectomy: a prospective cohort study

open access: yesFrontiers in Endocrinology
IntroductionAlthough active vitamin D (VD) has been used both preoperatively and postoperatively to prevent hypocalcemia risk in patients undergoing total thyroidectomy, the role of 1,25-dihydroxyvitamin D (1,25(OH)2D) has not been examined.
Hiroyuki Yamashita   +7 more
doaj   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Preoperative Circulating Tumor Cells (CTCs) Positivity is Associated with Lymph Node Metastasis in Patients with Unifocal Papillary Thyroid Microcarcinoma (PTMC)

open access: yesInternational Journal of General Medicine
Haifeng Zhong, Qingxin Zeng, Yuedong Wang, Jiwei Chen Department of Thyroid Surgery, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of ChinaCorrespondence: Jiwei Chen, Department of Thyroid Surgery, Meizhou ...
Zhong H, Zeng Q, Wang Y, Chen J
doaj  

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

Surgical Management of Recurrent Plasma Cell Mastitis in a Male Patient: A Case Report

open access: yesInternational Medical Case Reports Journal
Ting Yang,1 Haijiao Luo,2 Jing Zhou,1 Zhongxu Duan,1 Jingfeng Jing,1 Han Gao1 1Department of Breast and Thyroid, Women and Children’s Hospital of Chongqing Medical University: Chongqing Health Center for Women and Children, Chongqing, People’s Republic ...
Yang T   +5 more
doaj  

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