Results 191 to 200 of about 74,876 (285)

Pre‐RAI Monocyte‐to‐Lymphocyte Ratio Predicts Early and Higher Recurrence Risk in Intermediate‐Risk DTC, While PNI and NRI Show No Prognostic Value

open access: yesClinical Endocrinology, Volume 104, Issue 6, Page 670-681, June 2026.
ABSTRACT Objective Differentiated thyroid carcinoma (DTC) has an excellent prognosis, but recurrence remains a clinical concern, especially in intermediate‐risk patients. Current stratification systems focus primarily on tumor characteristics, overlooking the host's biological capacity to counteract tumor progression.
Tommaso Piticchio   +11 more
wiley   +1 more source

PAX8‐positive conventional urothelial carcinomas of the urinary bladder and their distinct molecular profiles – A clinicopathologic study of 101 consecutive cases with next‐generation sequencing in 20 cases

open access: yesHistopathology, Volume 88, Issue 7, Page 1315-1323, June 2026.
PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert   +5 more
wiley   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

open access: yesHistopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends   +48 more
wiley   +1 more source

Glucagon-like peptide-1 receptor (GLP-1R) overexpression defines a distinct immunogenetic subset in primary and metastatic thyroid cancer: implications for GLP-1R agonist therapy. [PDF]

open access: yesFront Oncol
Kennedy S   +11 more
europepmc   +1 more source

METTL3/YTHDF1‐Driven SURF6 Promotes Prostate Cancer Stemness via CDK4

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Prostate cancer (PCa) remains a major health challenge globally, necessitating the identification of novel therapeutic targets to improve patient outcomes. This study investigates the role of the SURF6 gene in PCa, focusing on its expression patterns, molecular mechanisms, and biological behaviours in vitro and in vivo.
Yue Cheng   +3 more
wiley   +1 more source

Isolation and functional characterization of primary human proximal tubular epithelial cells from brain‐dead organ donors

open access: yesPhysiological Reports, Volume 14, Issue 11, June 2026.
Protocol for isolation and culture of primary proximal tubular epithelial cells from kidneys retrieved from brain‐dead organ donors and designated for research after rejection for transplantation. These cells, bbd‐PTEC, express canonical proximal tubule epithelial markers and demonstrate functional transport.
Daiki Aomura   +6 more
wiley   +1 more source

Development of Graves orbitopathy after thyroidectomy for thyroid cancer. [PDF]

open access: yesJCEM Case Rep
Hormiz M   +5 more
europepmc   +1 more source

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