Results 171 to 180 of about 74,876 (285)

Deciphering nodal burden in thyroid carcinoma: A dedicated survey of age, lymph node ratio, log odds of positive nodes, and preoperative prediction models

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 2, Page 169-191, June 2026.
Abstract Evidence regarding the prognosis of thyroid carcinoma is heterogeneous, ranging from age effects and nodal burden metrics, such as lymph node ratio (LNR) and log odds of positive nodes (LODDS), to preoperative imaging models comprising ultrasound, CEUS, and radiomics.
Mennatallah Sherif   +2 more
wiley   +1 more source

Control of DNA replication by NCOA4 protein in HeLa cells

open access: yes, 2009
This dissertation is focused on the functional characterization of NCOA4 protein, and in particular on its role in controlling DNA replication in HeLa cells.
Provitera, Livia
core  

ACR‐TIRADS Institution and Effect on Thyroid Surgeries in Veterans: A 10‐Year Retrospective Study

open access: yesThe Laryngoscope, Volume 136, Issue 6, Page 2820-2826, June 2026.
Following analysis of the adoption of ACR TI‐RADS at the VA Northern California Healthcare System, the number of thyroid ultrasounds and FNAs increased substantially, while the total number of thyroid surgeries remained relatively stable. Surgical practice trends towards more selective and less‐invasive management, with fewer total thyroidectomies for ...
Isabella W. Leon   +4 more
wiley   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

open access: yesMedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li   +6 more
wiley   +1 more source

Metabolic Regulation of Immune Responses: Molecular Mechanisms, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 6, June 2026.
FBP1 loss drives immune evasion and therapy resistance by enhancing glycolysis, STAT3 activation, and PD‐L1 expression, leading to T cell exhaustion and NK cell inhibition. FBP1 restoration, via LNP‐mRNA or epigenetic modulation, reverses these immunosuppressive effects, reactivates cytotoxic T cells, promotes M1 macrophage polarization, and enhances ...
Chunwei Li   +10 more
wiley   +1 more source

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

open access: yesMed Research, Volume 2, Issue 2, Page 204-213, June 2026.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao   +14 more
wiley   +1 more source

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