Results 171 to 180 of about 3,138,389 (246)

Could Subjective Cognitive Complaints Give the Facts of Objective Cognitive Impairments in Non‐Central Nervous System Cancer? A Systematic Review

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Introduction Non‐central nervous system (non‐CNS) cancer patients experienced cognitive impairment, both subjectively and objectively. However, they are only weakly correlated. Previous studies indicated that subjective cognitive complaints (SCCs) could be a distinct neural phenotype from objective neuropsychological function.
Chieh‐Ning Li   +2 more
wiley   +1 more source

Adjusted Risk Stratification of Indeterminate Thyroid Nodules Using the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI‐RADS)

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background The TI‐RADS guides the initial management of thyroid nodules, but the malignancy risk across different categories of cytologically indeterminate thyroid nodules (CITNs), particularly AUS and FN, remains unclear. Methods We reviewed thyroid FNA specimens diagnosed as AUS or FN with TI‐RADS scores of 3, 4, or 5 from 2017 to 2025 ...
Jessica Zhao   +8 more
wiley   +1 more source

UTMD Suppresses CSF‐1 to Drive Macrophage‐Mediated Ferroptosis in Papillary Thyroid Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT The tumor microenvironment (TME) of Papillary Thyroid Carcinoma (PTC), particularly the role of tumor‐associated macrophages (TAMs), contributes to therapeutic resistance. This study investigated whether ultrasound‐targeted microbubble destruction (UTMD), a non‐invasive physical modality, could reprogram the TME through modulation of TAMs and ...
Yanqiang Niu   +6 more
wiley   +1 more source

Single‐Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment Remodeling

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
Single‐cell RNA sequencing of anaplastic thyroid cancer (ATC) and aggressive papillary thyroid cancer (PTC) revealed coordinated tumor‐intrinsic and immune reprogramming during thyroid cancer dedifferentiation. ATC exhibited MAPK/PI3K co‐activation, p53 suppression, E2F activation, cytotoxic lymphocyte exhaustion, enhanced regulatory T‐cell ...
Saeko Tahara   +6 more
wiley   +1 more source

Interactions Between E3 Ubiquitin Ligases and Deubiquitinases in AKT Regulation: Implications in Skeletal Muscle Homeostasis

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT AKT (protein kinase B, PKB) coordinates the balance between anabolic and catabolic signaling in skeletal muscle through distinct ubiquitin chain types. Some E3 ubiquitin ligases (E3s) and deubiquitinases (DUBs) form stable binary complexes via non‐catalytic interfaces, adding a regulatory layer unavailable to either enzyme alone.
Rajesh Dabur
wiley   +1 more source

Asymptomatic Medullary Thyroid Carcinoma With Isolated Carcinoembryonic Antigen Elevation in a Patient With Chronic Kidney Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Medullary thyroid carcinoma (MTC) is rare and typically presents with a palpable nodule. We report a 64‐year‐old asymptomatic woman with chronic kidney disease (CKD) diagnosed with MTC after incidental procalcitonin elevation on routine labs, highlighting procalcitonin as an atypical clue and the need to distinguish tumor‐related from CKD ...
Orhan Altınyüzük   +3 more
wiley   +1 more source

Interobserver variation among cytopathologists in the evaluation of oncocytic cell‐predominant thyroid FNA cytology: A validation study of 173 cases with surgical follow‐up and correlation with molecular testing

open access: yesCancer Cytopathology, Volume 134, Issue 9, September 2026.
Abstract Background Interpretation of oncocytic cell‐predominant cytologies (OCP) is very challenging as a majority of those cases are diagnosed as indeterminate, including atypia of undetermined significance (AUS) and follicular neoplasm (FN). The authors previously reported a combination of a four‐risk factor model highly predictive of neoplasia and ...
Tarik M. Elsheikh   +5 more
wiley   +1 more source

Comprehensive In Silico Analysis Identifies MSTO1 and LIG1 as Candidate Biomarkers With Diagnostic and Prognostic Relevance in Hepatocellular Carcinoma

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and remains a major cause of cancer‐related mortality worldwide. Its poor clinical outcomes are largely attributed to late‐stage diagnosis and the limited accuracy of currently available diagnostic and prognostic biomarkers.
Jana Hamad   +2 more
wiley   +1 more source

Prognostic Factor Analysis for Risk‐Stratified Papillary Thyroid Carcinoma and Nomogram Development for Predicting Structural Incomplete Response to Radioactive Iodine Therapy in Intermediate‐Risk Patients

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Structural incomplete response (SIR) after radioactive iodine (RAI) therapy indicates persistent or recurrent structural disease and has important implications for the long‐term management of patients with papillary thyroid carcinoma (PTC).
Yamin Li   +3 more
wiley   +1 more source

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