Results 71 to 80 of about 5,282,014 (364)

Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]

, 2014
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO, ERDAS, ENRICO, Medas F, NICOLOSI, ANGELO, Pisano G, Podda F, Santa Cruz R   +6 more
core   +1 more source

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

Role of Heterotypic Neutrophil-in-Tumor Structure in the Prognosis of Patients With Buccal Mucosa Squamous Cell Carcinoma

Frontiers in Oncology, 2020
ObjectiveTo analyze the role of frequency of heterotypic neutrophil-in-tumor structure (FNiT) in the prognosis of patients with buccal mucosa squamous cell carcinoma (BMSCC).MethodsIn vitro, we cocultured BMSCC cell line-H157 with neutrophils to form ...
Jie Fan, Jie Fan, Qigen Fang, Yang Yang, Meng Cui, Ming Zhao, Jinxing Qi, Ruihua Luo, Wei Du, Wei Du, Shanting Liu, Qiang Sun   +11 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Frequency and significance of Ras, Tert promoter, and Braf mutations in cytologically indeterminate thyroid nodules: A monocentric case series at a tertiary-level Endocrinology unit [PDF]

, 2017
PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to ...
Barollo, Susi, Bertazza, Loris, CASAL IDE, Eric, Cavedon, Elisabetta, Censi, Simona, DE LAZZARI, Paola, Fassina, Ambrogio, Galuppini, Francesca, Iacobone, Maurizio, Mian, Caterina, Nacamulli, Davide, Pennelli, Gianmaria, Vianello, Federica, WATUTANTRIGE FERNANDO, Sara   +13 more
core   +2 more sources

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na, Su Jin Choi, Sojeong Park, Minae Park, Doo‐Ho Lim   +4 more
wiley   +1 more source

Diagnosis and treatment of ectopic thyroid carcinoma: A case report and literature review

Frontiers in Oncology, 2022
IntroductionEctopic thyroid cancer (ETC) is primary thyroid cancer occurring in ectopic thyroid tissue, and its incidence rate is approximately 0.3%–0.5% of thyroid cancer.
Guiming Fu, Guiming Fu, Fengli Guo, Fengli Guo, Wei Zhang, Wei Zhang, Wei Zhang, Xianhui Ruan, Xiangqian Zheng, Zhaohui Wang, Ming Gao, Ming Gao, Ming Gao   +12 more
doaj   +1 more source

Thyroid ultrasonography reporting: consensus of Italian Thyroid Association (AIT), Italian Society of Endocrinology (SIE), Italian Society of Ultrasonography in Medicine and Biology (SIUMB) and Ultrasound Chapter of Italian Society of Medical Radiology (SIRM) [PDF]

, 2018
Thyroid ultrasonography (US) is the gold standard for thyroid imaging and its widespread use is due to an optimal spatial resolution for superficial anatomic structures, a low cost and the lack of health risks.
Cantisani, V., Chiovato, L., Durante, C., Farina, R., Frasoldati, A., Garberoglio, R., Ianni, F., Pontecorvi, A., Rago, T., Spiezia, S., Vallone, G., Vitti, P.   +11 more
core   +1 more source

Trends in Dermato‐polymyositis Mortality, 1999‐2022: A Nationwide Population‐based Study, United States

Arthritis Care &Research, Accepted Article.
Objective We evaluated trends in dermato‐polymyositis (DPM) mortality relative to all‐cause mortality in the United States, 1999‐2022. Methods We used the Center for Disease Control and Prevention's databases (Multiple Causes of Death for 1999‐2020 and Provisional Mortality Statistics for 2021 and 2022) to obtain death counts for DPM and non‐DPM (all ...
Elizabeth Matz, Ram R. Singh
wiley   +1 more source