Results 41 to 50 of about 938,886 (254)

Distribution of histopathological types of thyroid tumors in 1999-2015 compared to 1966-1988 year period [PDF]

Archive of Oncology, 2020
Background: The most common thyroid tumors originate from the epithelial follicular cells. Etiology involved in the development of thyroid carcinoma is multifactorial, including external influences and genetic predisposition.
Makazlieva Tanja, Vaskova Olivija, Nikolovska Aleksandra, Velikj Stefanovska Vesna   +3 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Case reports of collision and composite carcinomas of the thyroid: an insight into their origin and clinical significance

BMC Endocrine Disorders, 2023
Background Collision and composite carcinomas of the thyroid are extremely rare, and their clinical and biological characteristics are poorly understood.
Tao Ma, Ruixiao Wang, Xu Zhou, Liqiang Liu, Aijing Pan, Hongmei Wang, Lingyan Huang   +6 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Potential functions and mechanisms of lysine crotonylation modification (Kcr) in tumorigenesis and lymphatic metastasis of papillary thyroid cancer (PTC)

Journal of Translational Medicine
Objectives To examine the putative functions and mechanisms of lysine crotonylation (Kcr) during the development and progression of papillary thyroid cancer (PTC).
Zhaokun Li, Jingting Li, Fang Li, Liang Han, Chengqiu Sui, Le Zhou, Daqi Zhang, Yantao Fu, Rui Du, Jiedong Kou, Gianlorenzo Dionigi, Hui Sun, Nan Liang   +12 more
doaj   +1 more source

Simultaneous occurrence of medullary and papillary thyroid microcarcinomas: a case series and review of the literature

Journal of Medical Case Reports, 2013
Introduction Papillary thyroid microcarcinoma has been demonstrated to present in association with medullary thyroid carcinoma, however, medullary thyroid carcinoma and papillary thyroid carcinoma represent rare entities.
Adnan Zaina, Arad Eldad, Dana James, Shendler Yaakov, Baron Elzbieta   +4 more
doaj   +1 more source

Assessment of Papillary Thyroid Carcinoma with Ultrasound Examination

, 2022
Ultrasound examination of the thyroid is useful for preoperative assessment of thyroid nodules including papillary thyroid carcinoma. The examination mainly is to determine the malignant potential of thyroid nodule(s).
Lam, AK, Abe, I
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Role of Twist1 transcription factor in thyroid tumor progression [PDF]

, 2011
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core   +1 more source

Elucidating the role of Pyroptosis in papillary thyroid cancer: prognostic, immunological, and therapeutic perspectives

Cancer Cell International
Background Pyroptosis, an inflammatory form of programmed cell death, has been implicated in the pathogenesis and progression of several cancers. However, the significance of pyroptosis-related genes (PRGs) in papillary thyroid cancer (PTC) remains ...
Fang Li, Rui Du, Jiedong Kou, Jingting Li, Le Zhou, Daqi Zhang, Yantao Fu, Gianlorenzo Dionigi, Simona Bertoli, Hui Sun, Nan Liang   +10 more
doaj   +1 more source