Results 71 to 80 of about 938,886 (254)

Electrochemical Pathways for Nitrate Conversion to Ammonia: From Environmental Challenges to Ammonia Economy

Advanced Functional Materials, EarlyView.
This perspective presents recent advances in electrocatalytic nitrate reduction, focusing on reaction mechanisms, catalyst design, and electrolyzer configurations. Key challenges in selectivity, stability, and practical wastewater treatment are highlighted, while future directions for advancing sustainable ammonia synthesis and nitrate remediation are ...
Xintong Li, Yunpeng Zuo, Xiaoran Zhang, Jieqiong Shan, Kenneth Mei Yee Leung, Bin Liu, Peter Strasser, Adrian Fisher, Zonglong Zhu, Xin Wang   +9 more
wiley   +1 more source

Uncovering the connection between obesity and thyroid cancer: the therapeutic potential of adiponectin receptor agonist in the AdipoR2-ULK axis

Cell Death and Disease
Adiponectin, a unique adipose-derived factor, is significantly downregulated in obesity, making it a crucial target for tumor-related metabolic research.
Changlin Li, Jiao Zhang, Gianlorenzo Dionigi, Nan Liang, Haixia Guan, Hui Sun   +5 more
doaj   +1 more source

Critically evaluated key points on hereditary medullary thyroid carcinoma

Frontiers in Endocrinology
Medullary thyroid carcinoma (MTC) accounts for only 3% of all thyroid carcinomas: 75% as sporadic MTC (sMTC) and 25% as hereditary MTC (hMTC) in the context of multiple endocrine neoplasia type 2 (MEN2).
Daqi Zhang, Nan Liang, Hui Sun, Francesco Frattini, Chengqiu Sui, Mingyu Yang, Hongbo Wang, Gianlorenzo Dionigi, Gianlorenzo Dionigi   +8 more
doaj   +1 more source

miR‐671‐5p repressed progression of papillary thyroid carcinoma via TRIM14

Kaohsiung Journal of Medical Sciences, 2021
The pivotal role of dysregulated miRNAs in development of papillary thyroid carcinoma has been emphasized in recent research. miR‐671‐5p was previously documented to function as a tumor suppressor.
Wan‐Ju Wang, Yuan Yuan, Dong Zhang, Piao Liu, Fang Liu   +4 more
doaj   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

Advanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad, Anastasiia Steksova, Yuyang Tang, Leyao Huang, Alireza Velayati, Shengwei Zhang, Aditi Dey Poonam, Sina Jamalzadegan, Matthew Breen, Hongjie Chen, Mahsa Bagi, Guochun Jiang, Qingshan Wei   +12 more
wiley   +1 more source

Parathyroid Double Adenoma Associated with Papillary Carcinoma of Thyroid [PDF]

It has been reported that thyroid disease is common in patients with hyperparathyroidism, and vice versa. Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT).
دادخواه, مینو, ایرانپرور, منوچهر, پورفرضی, فرهاد, رستمی, خلیل   +3 more
core  

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Update on epidemiology classification, and management of thyroid cancer [PDF]

Libyan Journal of Medicine, 2006
Thyroid cancer represents approximately 0.5–1% of all human malignancy1. In the UK the incidence of thyroid cancer is 2-3 per 100,000 populations 2. In geographical areas of low iodine intake and in areas exposed to nuclear disasters the incidence of ...
Heitham Gheriani
doaj  

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

Advanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku, Jinwon Kwon, Nara Yoon, Hyung Kwon Byeon, Jaemoon Yang   +4 more
wiley   +1 more source