Results 91 to 100 of about 286,078 (313)

Thyroid Hormone Resistance Syndromes

open access: yes, 2019
Syndromes with impaired sensitivity to thyroid hormone (TH) include three types of resistance to thyroid hormone (RTH) syndromes (RTHβ, RTHα, and nonTR-RTH) and also include patients with defects in TH transport into cells (thyroid hormone cell membrane ...
Refetoff, Samuel   +3 more
core   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

Thyroid diseases : Advances on diagnosis and treatment. Diagnosis of thyroid diseases. Promotion of diagnosis of thyroid diseases.

open access: yesNihon Naika Gakkai Zasshi, 1997
甲状腺疾患の診断・治療はホルモンや抗体の微量測定が進歩したおかげで,大変楽になった様に見える.しかし,患者を前にして,問診,触診,考えながら検査を選ぶ重要性は昔も今も変わらない.このような意味で,問診の段階から検査の選択まで,出来る限り現場の実際に即した形で,診断の要点を記載したつもりである.甲状腺ホルモンの組織における作用に良いindicatorのない現状では,症候や理学所見からのスケーリングが大切なことも理解していただきたいと思う.
openaire   +2 more sources

Pharmacological aspects of thyroid disease treatment

open access: yes, 2019
Diseases affecting the thyroid gland can severely affect the functioning and quality of life of patients therefore it is important to be aware as early detection of diseases usually produce better outcomes.
Asemota, Faith Osarugue
core  

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Preoperative serum indicators as predictors of postoperative hypoparathyroidism following thyroidectomy

open access: yesFrontiers in Endocrinology
BackgroundHypoparathyroidism is a frequent complication following thyroidectomy. However, the risk factors for postoperative hypoparathyroidism remain poorly characterized.
Kailin Liu   +6 more
doaj   +1 more source

Thyroid disorders in India: An epidemiological perspective

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Thyroid diseases are common worldwide. In India too, there is a significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid ...
Ambika Gopalakrishnan Unnikrishnan   +1 more
doaj   +1 more source

Immunological mechanisms controlling chronic inflammatory diseases

open access: yes, 2009
Autoimmune diseases (AID) are chronic inflammatory diseases (CID) mediated by self-reactive T and B cells and are generally the results of the breakdown of T cell tolerance to self-antigen and failure of peripheral regulatory mechanisms. In this thesis I
Cexus, Olivier
core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Single-cell transcriptomics analysis reveals that the tumor-infiltrating B cells determine the indolent fate of papillary thyroid carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research
Objective Active surveillance (AS) offers a viable alternative to surgical intervention for the management of indolent papillary thyroid carcinoma (PTC), helping to minimize the incidence of unnecessary treatment.
Chunmei Li   +11 more
doaj   +1 more source

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