Results 101 to 110 of about 286,078 (313)

Thyroid and Heart: A Fatal Pathophysiological Attraction in a Controversial Clinical Liaison

, 2023
The thyroid–heart relationship has a long and articulated history of its own, a history that encompasses physiological and pathophysiological knowledge.
Cristina Vassalle, Alessandro Pingitore, Maria Francesca Lodovica Lazzeri, Francesca Mastorci   +3 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Causal effect of thyroid cancer on secondary primary malignancies: findings from the UK Biobank and FinnGen cohorts

Frontiers in Immunology
BackgroundExisting epidemiological data indicated a correlation between thyroid cancer (THCA) and the risk of secondary primary malignancies (SPMs). However, the correlation does not always imply causality.MethodsThe Mendelian randomization (MR) analyses
Zhengshi Wang, Zhengshi Wang, Youlutuziayi Rixiati, Chengyou Jia, Yong Xu, Zhiqiang Yin, Zhiqiang Yin, Junwen Huang, Junwen Huang, Jiaqi Dai, Jiaqi Dai, Yun Zhang, Yun Zhang   +12 more
doaj   +1 more source

Role of Estrogen in Thyroid Function and Growth Regulation [PDF]

, 2011
Thyroid diseases are more prevalent in women, particularly between puberty and menopause. It is wellknown that estrogen (E) has indirect effects on the thyroid economy.
Ana Paula Santin, Furlanetto, Tania Weber, Santin, Ana Paula, Tania Weber Furlanetto   +3 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

The zebrafish model to identify new genes involved in thyroid development

, 2010
Thyroid organogenesis is a very complex developmental process that leads to the formation of an organ able to produce specific hormones through specification, migration, structural organization and functional differentiation of thyroid precursor cells ...
Porreca, Immacolata
core  

Are Perinatal Events Risk Factors for Childhood Thyroid Autoimmunity?

, 2017
Background: Environmental and genetic factors possibly trigger thyroid autoimmunity. Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse.
Lernmark, Åke,, Elding Larsson, Helena,, Jonsdottir, Berglind,, Wallengren, Sara,, Jönsson, Ida,, Lundgren, Markus,, Lund University., DiPiS Study Group   +7 more
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

SURGICAL TREATMENT OF THYROID DISEASES IN ELDERLY PATIENTS

, 2010
BACKGROUND: We evaluated the safety of thyroid surgery in elderly patients, in whom surgical procedures usually are considered more hazardous than in younger patients.
Princi, Pietro, Rossi, Esther, De Crea, Carmela, Bellantone, Rocco Domenico Alfonso, Raffaelli, Marco, Fadda, Guido, Lombardi, Celestino Pio   +6 more
core  

Autoimmune diseases of the thyroid gland [PDF]

, 2022
Background: The aim of this work is to provide a comprehensive overview of thyroid diseases, especially the group of autoimmune diseases, summarize the mechanisms of autoimmunity, physiology of the thyroid gland, introduce selected diseases and the ...
Šlapáková, Tereza
core