Results 81 to 90 of about 2,705,771 (305)

Immunological mechanisms controlling chronic inflammatory diseases

open access: yes, 2009
Autoimmune diseases (AID) are chronic inflammatory diseases (CID) mediated by self-reactive T and B cells and are generally the results of the breakdown of T cell tolerance to self-antigen and failure of peripheral regulatory mechanisms. In this thesis I
Cexus, Olivier
core   +1 more source

Integrative Analyses of Mitophagy-Related Genes and Mechanisms Associated with Type 2 Diabetes in Muscle Tissue

open access: yesCurrent Issues in Molecular Biology
Type 2 diabetes (T2D) represents the most prevalent metabolic condition that is primarily distinguished by a range of metabolic imbalances, including hyperglycemia, hyperlipidemia, and insulin resistance (IR). Currently, mitophagy has become increasingly
Wangjia Mao   +4 more
doaj   +1 more source

Thyroid diseases : Advances on diagnosis and treatment. Diagnosis of thyroid diseases. Promotion of diagnosis of thyroid diseases.

open access: yesNihon Naika Gakkai Zasshi, 1997
甲状腺疾患の診断・治療はホルモンや抗体の微量測定が進歩したおかげで,大変楽になった様に見える.しかし,患者を前にして,問診,触診,考えながら検査を選ぶ重要性は昔も今も変わらない.このような意味で,問診の段階から検査の選択まで,出来る限り現場の実際に即した形で,診断の要点を記載したつもりである.甲状腺ホルモンの組織における作用に良いindicatorのない現状では,症候や理学所見からのスケーリングが大切なことも理解していただきたいと思う.
openaire   +2 more sources

Robotic Surgery for Thyroid Disease [PDF]

open access: yes, 2013
Robotic surgery is an innovation in thyroid surgery that may compensate for the drawbacks of conventional endoscopic surgery. A surgical robot provides strong advantages, including three-dimensional imaging, motion scaling, tremor elimination, and ...
정웅윤
core   +1 more source

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease‐Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan‐Cytology Validation

open access: yesAdvanced Science, EarlyView.
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong   +14 more
wiley   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He   +10 more
wiley   +1 more source

The relationship between the diagnostic performance of dual-energy CT quantitative parameters in thyroid cancer, cervical lymph node metastasis and prognosis

open access: yesBMC Endocrine Disorders
Objective This study aims to investigate the relationship between quantitative parameters of dual-energy computed tomography (DECT) and its diagnostic performance in thyroid cancer, cervical lymph node metastasis, and prognosis.
Guangxi Liang   +3 more
doaj   +1 more source

Preoperative serum indicators as predictors of postoperative hypoparathyroidism following thyroidectomy

open access: yesFrontiers in Endocrinology
BackgroundHypoparathyroidism is a frequent complication following thyroidectomy. However, the risk factors for postoperative hypoparathyroidism remain poorly characterized.
Kailin Liu   +6 more
doaj   +1 more source

Thyroid disorders in India: An epidemiological perspective

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Thyroid diseases are common worldwide. In India too, there is a significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid ...
Ambika Gopalakrishnan Unnikrishnan   +1 more
doaj   +1 more source

Caveolin-1 is required for proper hormone synthesis in thyroid follicles.

open access: yes, 2010
Caveolin-1 down-regulates thyroid cell proliferation.
Van Regemorter, Victoria   +1 more
core  

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