Results 61 to 70 of about 2,705,771 (305)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Carotid‐Type Eagle Syndrome: Successful Management With Transcervical Styloidectomy: A Case Report

Clinical Case Reports
Carotid‐type Eagle syndrome should be considered in patients with unexplained presyncope, particularly when symptoms are position‐dependent. High‐resolution CT is essential for identifying elongated styloid processes and their relationship to the carotid
Cristhian Garcia, Jessica Cayambe, Ana Perez, Fernanda Zambonino, Mikaela Garcia, Eduardo Pilatuna, Paola Solis‐Pazmino   +6 more
doaj   +1 more source

Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2018
Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development of thyroid diseases. Thyroid function, represented
Yul Hwangbo, Young Joo Park
doaj   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Ameliorative effect and mechanism of ursodeoxycholic acid on hydrogen peroxide-induced hepatocyte injury

Scientific Reports
To assess the ameliorative effect of ursodeoxycholic acid (UDCA) on hydrogen peroxide (H2O2)-induced hepatocyte injury. In our in vivo experiments, we modelled hyperlipidemia in ApoE−/− mice subjected to a 3-month high-fat diet and found that HE staining
Xueqin Wang, Guangxi Liang, Yang Zhou, Banggao Ni, Xiangyu Zhou   +4 more
doaj   +1 more source

Estimating global prevalence of gallbladder stones in general population from 2000 to 2024: systematic review and meta-analysis

Annals of Medicine
Background Gallbladder stones (GS), is one of the most common and costly of all the gastrointestinal diseases. However, global prevalence estimates of GS remain heterogeneous due to methodological variations across studies, and consensus on risk factor ...
Qingyang Ning, Fen Liu, Yiqiao Fang, Xixi Zhu, Jiaye Liu, Zhihui Li   +5 more
doaj   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Thyroid diseases : Advances on diagnosis and treatment. Diagnosis of thyroid diseases. Imaging of thyroid diseases.

Nihon Naika Gakkai Zasshi, 1997
甲状腺腫の性状の評価には超音波検査(US)がもっとも広く行われている.結節を高感度に検出し,特に腺腫様甲状腺腫の診断に有用である.甲状腺中毒症の原因検索のため123Iまたは99mTc甲状腺シンチグラフィーが行われる.特にバセドウ病と無痛性甲状腺炎との鑑別に有用である.可逆性甲状腺機能低下症では摂取率高値を示す.分化型甲状腺癌の転移巣の早期発見は131I治療効果を考えた場合重要であり,最近開発された99mTc-MIBIが注目されている.
openaire   +2 more sources

Immunohistochemistry differentiates papillary thyroid carcinoma arising in ectopic thyroid tissue from secondary lymph node metastases.

, 2007
Objective: To verify whether immunohistochemistry might be useful in the distinction between a true laterocervical metastasis of an undetected thyroid carcinoma and a primary tumor outside the gland.
ARAGONA, Federico, CACCIATORE M, THYROID JUL, CABIBI, Daniela, GUARNOTTA, Carla   +4 more
core   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu, Peng Guo, Rui Pan, Zhenghao Wang, Jingchao Zhou, Pengcheng Zhang, Xingzhe Zhang, Qinghua Zhang, Haibin Ma, Zhanfeng Niu   +9 more
wiley   +1 more source