Results 61 to 70 of about 2,558,886 (304)

Imaging and Laboratory Approach to Thyroid Diseases

open access: yes, 2020
Thyroid function tests need for estimating functional activity of thyroid gland and autoantibodies support for diagnosis of thyroid dysfunction. FNA and molecular testing are used as confirmation examination for thyroid malignancy.
Michihiro, Mayu
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Thyroid diseases : Advances on diagnosis and treatment. Diagnosis of thyroid diseases. Imaging of thyroid diseases.

open access: yesNihon Naika Gakkai Zasshi, 1997
甲状腺腫の性状の評価には超音波検査(US)がもっとも広く行われている.結節を高感度に検出し,特に腺腫様甲状腺腫の診断に有用である.甲状腺中毒症の原因検索のため123Iまたは99mTc甲状腺シンチグラフィーが行われる.特にバセドウ病と無痛性甲状腺炎との鑑別に有用である.可逆性甲状腺機能低下症では摂取率高値を示す.分化型甲状腺癌の転移巣の早期発見は131I治療効果を考えた場合重要であり,最近開発された99mTc-MIBIが注目されている.
openaire   +2 more sources

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Clinical and Pathological Implications of Concurrent Autoimmune Thyroid Disorders and Papillary Thyroid Cancer [PDF]

open access: yes, 2011
Cooccurrences of chronic lymphocytic thyroiditis (CLT) and thyroid cancer (DTC) have been repeatedly reported. Both CLT and DTC, mainly papillary thyroid carcinoma (PTC), share some epidemiological and molecular features.
Vassallo, J   +14 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Systemic lupus erythematosus and thyroid disease – Experience in a single medical center in Taiwan

open access: yesJournal of Microbiology, Immunology and Infection, 2019
Background: To investigate the association of systemic lupus erythematosus (SLE) with thyroid diseases in a medical center in central Taiwan. Methods: This is a retrospective cohort of 2796 SLE patients in a tertiary referral medical center from 2000 to ...
Yu-chuan Liu   +3 more
doaj   +1 more source

Novel associations for hypothyroidism include known autoimmune risk loci [PDF]

open access: yes, 2011
Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the first large genome-wide association study of hypothyroidism, in 2,564 cases and 24,448 controls from the customer base of 23andMe, Inc.,
Amy K. Kiefer (160836)   +25 more
core   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

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