Results 51 to 60 of about 286,078 (313)

Subclinical Thyroid Disease [PDF]

Mayo Clinic Proceedings, 2001
The term subclinical thyroid disease is used to describe asymptomatic thyroid abnormalities found on imaging studies or laboratory tests. Thyroid nodules not palpable on physical examination but detected on imaging studies performed for other purposes are called incidentalomas.
openaire   +2 more sources

The thyroid gland in postmenopausal women: physiology and diseases

, 2017
The incidence of most thyroid diseases: hypothyroidism, nodular goitre, and cancer is highest among postmenopausal and elderly women. The diagnosis of thyroid dysfunction in this group of patients is difficult because the symptoms can be nonspecific or ...
Małgorzata Gietka-Czernel
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Indonesian Clinical Practice Guidelines for Hyperthyroidism

Journal of the ASEAN Federation of Endocrine Societies, 2014
Hyperthyroidism remains as one of the major thyroid disorders in Indonesia.The Indonesian Task Force on Thyroid Diseases determined that hyperthyroidism represents a priority area in need of updated evidence-based practice guidelines.The aim of the ...
The Indonesian Society of Endocrinology Task Force on Thyroid Diseases
doaj  

Association between lymphocyte to high-density lipoprotein cholesterol ratio and insulin resistance and metabolic syndrome in US adults: results from NHANES 2007–2018

Lipids in Health and Disease
Background Insulin resistance (IR) and metabolic syndrome (MetS) are significant global health challenges that increase the risk of various chronic diseases.
Junwei Guo, Kelibinuer Mutailipu, Xin Wen, Jiajing Yin, Hui You, Shen Qu, Haibing Chen, Le Bu   +7 more
doaj   +1 more source

Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases. [PDF]

Nat Genet
Thyroid diseases are common and highly heritable. We performed a metaanalysis of genome-wide association studies from 19 biobanks for five thyroid diseases: thyroid cancer, benign nodular goiter, Graves' disease, lymphocytic thyroiditis, and primary ...
White SL, Brasher MS, Pattee J, Zhou W, Chapman S, Jee YH, Bell CC, Jamil TL, Barrio M, Arehart CH, Evans LM, Hirbo J, Cox NJ, Straub P, Namba S, Bertucci-Richter E, Guare L, Edris A, Morris S, Mulford AJ, Zhang H, Fennessy B, Tobin MD, Chen J, Williams AT, John C, van Heel DA, Mathur R, Finer S, Moksnes MR, Brumpton BM, Åsvold BO, Peculis R, Rovite V, Konrade I, Wang Y, Crooks K, Chavan S, Fisher MJ, Rafaels N, Lin M, Shortt JA, Sanders AR, Whiteman DC, MacGregor S, Medland SE, Thorsteinsdóttir U, Stefánsson K, Karaderi T, Egan KM, Bocklage T, McCrary HC, Riedlinger G, Salhia B, Shriver C, Phan MD, Farlow JL, Edge S, Kaur V, Churchman ML, Rounbehler RJ, Brock PL, Ringel MD, Pividori M, Schweppe R, Raeburn CD, Walters RG, Chen Z, Li L, Matsuda K, Okada Y, Zöllner S, Verma A, Penn Medicine BioBank, Preuss MH, Kenny E, Hendricks AE, Fishbein L, Kraft P, Daly MJ, Neale BM, Virtual Thyroid Biopsy Consortium, Colorado Center for Personalized Medicine, Genes & Health Research Team, BioBank Japan Project, Martin AR, Cole JB, Haugen BR, Global Biobank Meta-analysis Initiative, Gignoux CR, Pozdeyev N.   +90 more
europepmc   +2 more sources

Anemia in thyroid diseases

Polish Archives of Internal Medicine, 2017
Anemia is a frequent, although often underestimated, clinical condition accompanying thyroid diseases. Despite the fact that anemia and thyroid dysfunction often occur simultaneously, the causative relationship between the disorders remains ambiguous.
Ewelina, Szczepanek-Parulska, Aleksandra, Hernik, Marek, Ruchała   +2 more
openaire   +2 more sources

Changes in Drug Clinical Trials of Thyroid Diseases in China, 2009–2022

, 2023
Chen Li,1,* Jun Hao,2,* Chuangshi Wang,2 Jie Yang,1 Yitian Zheng,1 Kuo Zhang,3 Wen Hui,4 Xiangbin Meng,1 Jun Gao,1 Wei Li,2 Yi-Da Tang1,5 1Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; Key ...
Li W, Yang J, Zheng Y, Li C, Hao J, Zhang K, Wang C, Gao J, Tang YD, Hui W, Meng X   +10 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Molecular mechanism of thyroxine transport by monocarboxylate transporters

Nature Communications
Thyroid hormones (the common name for prohormone thyroxine and the bioactive form triiodothyronine) control major developmental and metabolic processes.
Matteo Tassinari, Giorgia Tanzi, Francesco Maggiore, Stefan Groeneweg, Ferdy S. van Geest, Matthijs E. T. Freund, Christiaan J. Stavast, Irene Boniardi, Sebastiano Pasqualato, W. Edward Visser, Francesca Coscia   +10 more
doaj   +1 more source