Results 51 to 60 of about 2,558,886 (304)

Peptide receptor radionuclide therapy in patients with medullary thyroid carcinoma: predictors and pitfalls

open access: yesBMC Cancer, 2019
Background For progressive metastatic medullary thyroid carcinoma (MTC), the available treatment options with tyrosine kinase inhibitors result in grade 3–4 adverse events in a large number of patients. Peptide Receptor Radionuclide Therapy (PRRT), which
Carolien M. Beukhof   +11 more
doaj   +1 more source

Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer [PDF]

open access: yesEndocrinology and Metabolism, 2018
Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development of thyroid diseases. Thyroid function, represented
Yul Hwangbo, Young Joo Park
doaj   +1 more source

STUDIES ON THE THYROID DISEASES

open access: yesNihon Naika Gakkai Zasshi, 1964
The present report deals with the studies on the epidemiology, etiology, diagnosis, clinical pathology and treatment of thyroid diseases in my clinic.
openaire   +4 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Immunological mechanisms controlling chronic inflammatory diseases

open access: yes, 2009
Autoimmune diseases (AID) are chronic inflammatory diseases (CID) mediated by self-reactive T and B cells and are generally the results of the breakdown of T cell tolerance to self-antigen and failure of peripheral regulatory mechanisms. In this thesis I
Cexus, Olivier
core   +1 more source

Carotid‐Type Eagle Syndrome: Successful Management With Transcervical Styloidectomy: A Case Report

open access: yesClinical Case Reports
Carotid‐type Eagle syndrome should be considered in patients with unexplained presyncope, particularly when symptoms are position‐dependent. High‐resolution CT is essential for identifying elongated styloid processes and their relationship to the carotid
Cristhian Garcia   +6 more
doaj   +1 more source

Thyroid Disease and Lipids

open access: yesThyroid, 2002
The composition and the transport of lipoproteins are seriously disturbed in thyroid diseases. Overt hypothyroidism is characterized by hypercholesterolaemia and a marked increase in low-density lipoproteins (LDL) and apolipoprotein B (apo A) because of a decreased fractional clearance of LDL by a reduced number of LDL receptors in the liver.
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Ameliorative effect and mechanism of ursodeoxycholic acid on hydrogen peroxide-induced hepatocyte injury

open access: yesScientific Reports
To assess the ameliorative effect of ursodeoxycholic acid (UDCA) on hydrogen peroxide (H2O2)-induced hepatocyte injury. In our in vivo experiments, we modelled hyperlipidemia in ApoE−/− mice subjected to a 3-month high-fat diet and found that HE staining
Xueqin Wang   +4 more
doaj   +1 more source

Estimating global prevalence of gallbladder stones in general population from 2000 to 2024: systematic review and meta-analysis

open access: yesAnnals of Medicine
Background Gallbladder stones (GS), is one of the most common and costly of all the gastrointestinal diseases. However, global prevalence estimates of GS remain heterogeneous due to methodological variations across studies, and consensus on risk factor ...
Qingyang Ning   +5 more
doaj   +1 more source

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