Results 101 to 110 of about 442,297 (356)

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Research progress on fat mass and obesity-associated protein in obesity-related tumors [PDF]

Xin yixue
Fat mass and obesity-associated protein （FTO）， the first identified obesity-susceptibility gene， exerts complex roles in tumors via its RNA demethylase function.
LI Zelong, HUANG Junwei, CHEN Hao, YING Yong, XIE Yang, ZENG Xiangtai
doaj   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Evaluation of Patients with Thyroid Diseases in Baquba City According to Thyroid Function Tests

Diyala Journal of Medicine, 2019
Background: Thyroid gland is the largest endocrine gland which is consists of right and left lobes connected by a narrow isthmus, the weight of this gland is 10-20g in normal adult .The function of thyroid gland is to secret T3, T4 under control of TSH.
Ahmed M Athab Al-Msari , Ali Hussein Salih AL-Duleimy , Imad Ahmed Lateef   +2 more
doaj   +2 more sources

Evaluation of renal perfusion in hyperthyroid cats before and after radioiodine treatment [PDF]

, 2017
Background: Hyperthyroidism and chronic kidney disease (CKD) are common in elderly cats. Consequently, both diseases often occur concurrently. Furthermore, renal function is affected by thyroid status. Because changes in renal perfusion play an important
Adams, Adams, Becker, Boag, Brown, Daniel, Debruyn, Dong, Dong, Fischer, Gauthier, Graves, Grenier, Haers, Herget-Rosenthal, Hoek, Hoek, Hyvelin, Kay, Ma, Milner, Ohlerth, Paepe, Paepe, Peterson, Riensche, Slater, Stock, Stock, Stock, Tang, Tsuruoka, Vaske, Volckaert, Williams   +34 more
core   +2 more sources

Thyroid bone disease

Indian Journal of Medical Research, 2012
In this issue Jyotsna et al1 report the changes in bone mineral density (BMD) in predominantly 25(OH)D deficient patients with Graves disease. They have studied the thyroid functions, bone mineral parameters in serum and BMD before and after the achievement of euthyroid status in study group and related the hormonal changes to BMD.
openaire   +2 more sources

Comprehensive network pharmacology and experimentation to unveil the therapeutic efficacy and mechanisms of gypenoside LI in anaplastic thyroid cancer

BMC Cancer
Background Anaplastic thyroid cancer (ATC) is a markedly invasive subtype of thyroid cancer with a poor prognosis. The Gynostemma pentaphyllum-derived Gypenoside LI (Gyp LI) can inhibit the growth and metastasis of various tumors. This study was designed
Meiyu Liu, Haidong Liao, Qin Peng, Junwei Huang, Weixiang Liu, Mengqiao Dai, Zanbing Li, Yang Xie, Jiafeng Liu, Yong Ying, Xiangtai Zeng   +10 more
doaj   +1 more source

Impact of a simple informative leaflet on Brazilian doctors' attitudes towards active surveillance of thyroid microcarcinomas

Heliyon
Introduction: Active surveillance (AS) is increasingly recognized as an appropriate strategy for selected patients with papillary thyroid microcarcinomas (PTMC).
Fernanda Barbosa Duarte, Fernanda Nascimento Faro, Laura Sterian Ward, Adriano Namo Cury, Carolina Ferraz, Rosália do Prado Padovani   +5 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

A Cross-Sectional Study Examining the Parametric Thyroid Feedback Quantile Index and Its Relationship with Metabolic and Cardiovascular Diseases

, 2022
Vanesa Alonso‐Ventura, Fernando Civeira, Almendra Alvarado-Rosas, José Manuel Lou-Bonafonte, Pilar Calmarza, Belen Moreno-Franco, María Jesús Andrés-Otero, Fernando Calvo-Gracia, Patricia de Diego-Garcia, Martin Laclaustra   +9 more
openalex   +2 more sources