Results 151 to 160 of about 97,265 (298)
A Case of Severe Thyroid Eye Disease Treated with Tocilizumab [PDF]
Aysel Mehmet +7 more
openalex +1 more source
Abstract Background Craniospinal irradiation (CSI) is essential for treating pediatric medulloblastoma (MB) but causes significant long‐term toxicities. Existing dose‐reduction or partial‐sparing strategies improve neurocognitive outcomes but may compromise survival or fail to address other late effects.
Keqiang Wang +5 more
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Implementation of thyroid eye disease registry in Iran: rationale and research protocol
Background To describe the implementation of a registry system for patients with thyroid eye disease (TED) in Iran to obtain more information about its nature, prevalence, and annual incidence, as well as extend insight into the etiology, pathogenesis ...
Shadi Akbarian +5 more
doaj +1 more source
Analyses of risks associated with radiation exposure from past major solar particle events [PDF]
Radiation exposures and cancer induction/mortality risks were investigated for several major solar particle events (SPE's). The SPE's included are: February 1956, November 1960, August 1972, October 1989, and the September, August, and October 1989 ...
Atwell, William +4 more
core +1 more source
12231 PAPP-A As A Potential Target In Thyroid Eye Disease [PDF]
Cheryl A. Conover +3 more
openalex +1 more source
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio +12 more
wiley +1 more source

