Results 101 to 110 of about 467,067 (355)
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu+7 more
wiley +1 more source
Salicylates and Thyroid Function. II. The Effect on the Thyroid-Pituitary Interrelation [PDF]
J. Wolff, Frank Austen
openalex +1 more source
Reserpine and Thyroid Function
SummaryReserpine at the dose levels employed clinically for the treatment of hypertension does not affect thyroid function in man. The effects of large doses in the rat appear to be due to hypotensive effects and interference with the renal excretion of iodide.
Joseph R. Goodman+2 more
openaire +3 more sources
Profil Petani Sayur di Kabupaten Karanganyar Berdasarkan Kadar Kholinesterase dan Fungsi Tiroidnya [PDF]
Iodine is an essential mineral. This mineral is indispensable as thyroid forming substance, which is produced by the thyroid gland. The performance of the thyroid gland could be disrupted by the pesticide, when used excessively.
Fuada, N. (Noviati)+2 more
core +1 more source
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo+15 more
wiley +1 more source
The Concentration and Significance of the Butanol-Extractable I131 of Serum in Patients with Diverse States of Thyroidal Function [PDF]
Sidney H. Ingbar+3 more
openalex +1 more source
Thyroid function and postmenopause
There is an increasing prevalence of high levels of thyroid stimulating hormone (TSH) with age - particularly in postmenopausal women - which are higher than in men. The incidence of thyroid disease in a population of postmenopausal women is as follows: clinical thyroid disease, about 2.4%; subclinical thyroid disease, about 23.2%. Among the group with
openaire +3 more sources
Thyroid function in pregnancy [PDF]
Iodine is required for the production of thyroid hormones. Normal thyroid function during pregnancy is important for both the mother and developing fetus. This review discusses the changes in thyroid physiology that occur during pregnancy, the significance of thyroid function tests and thyroid antibody titers assessed during pregnancy, and the ...
openaire +3 more sources
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen+13 more
wiley +1 more source
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang+10 more
wiley +1 more source