Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes [PDF]
Objective: There remains controversy over how women with abnormal thyroid function tests in pregnancy should be classified. In this study we assessed the proportion of women with thyroid stimulating hormone (TSH) ≥ 2.5 mU/l in a large obstetric cohort,
Carty, David M.+4 more
core +1 more source
Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level [PDF]
Purpose: We designed our study to evaluate the hypothesis that gastric cancer is correlated with iodine deficiency or thyroid dysfunction. Materials and Methods: We investigated the total body iodine reserve, thyroid function status and autoimmune ...
Adabi, K.+12 more
core +1 more source
Excess iodine intake: sources, assessment, and effects on thyroid function
Iodine is essential for thyroid hormone synthesis. High iodine intakes are well tolerated by most healthy individuals, but in some people, excess iodine intakes may precipitate hyperthyroidism, hypothyroidism, goiter, and/or thyroid autoimmunity ...
J. Farebrother+2 more
semanticscholar +1 more source
Objective To investigate the influence of thyroid dysfunction on the antiviral efficacy of α-interferon in adult patients with chronic hepatitis B (CHB).
Wenfan Luo+4 more
doaj +1 more source
Interferences With Thyroid Function Immunoassays: Clinical Implications and Detection Algorithm
Automated immunoassays used to evaluate thyroid function are vulnerable to different types of interference that can affect clinical decisions. This review provides a detailed overview of the six main types of interference known to affect measurements of ...
J. Favresse+3 more
semanticscholar +1 more source
Background: Despite the use of routine thyroid function tests, thyroid dysfunction is often missed in pregnant women, who may have fluctuating iodine reserves and this may be associated with an increased risk of adverse maternal and fetal outcomes due to
Terry Terfa Gbaa
doaj +1 more source
Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]
The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć+2 more
core +1 more source
A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]
Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro+6 more
core +2 more sources
A hidden cause of infertility in hypothyroid patients [PDF]
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy+4 more
core +1 more source
Thyroid Function Test in COVID-19 Patients: A Cross-Sectional Study in a Tertiary Care Hospital
Context: There is scarcity of data on thyroid function abnormality in COVID-19 patients in world literature. Aims: The objective of this study was to assess thyroid function tests in hospitalized patients of COVID-19.
Kaushik Sen+4 more
doaj +1 more source