Results 31 to 40 of about 12,755,878 (352)

Considerations in evaluating the thyroid gland in a primary care setting

Journal of Family Medicine and Primary Care, 2020
The evaluation of the thyroid can be a very involved process. A misinterpretation of the results of a thyroid function test can lead to serious complexities in a patient's management and outcome.
Jose Humphreys
doaj   +1 more source

Low thyroid function is associated with an increased risk of advanced fibrosis in patients with metabolic dysfunction-associated fatty liver disease

BMC Gastroenterology, 2023
Aims Observational studies showed that low thyroid function may perturb liver function. We aimed to evaluate the association of low thyroid function with both metabolic dysfunction-associated fatty liver disease (MAFLD) and advanced hepatic fibrosis ...
Hong Fan, Lili Li, Zhenqiu Liu, Pengyan Zhang, Sheng Wu, Xinyu Han, Xingdong Chen, Chen Suo, Liou Cao, Tiejun Zhang   +9 more
doaj   +1 more source

Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]

, 2018
The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
core   +1 more source

Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study

International Journal of Cancer, 2020
Whether thyroid dysfunction plays a causal role in the development of cancer remains inconclusive. We conducted a two-sample Mendelian randomization study to investigate the associations between genetic predisposition to thyroid dysfunction and 22 site ...
S. Yuan, S. Kar, M. Vithayathil, Paul Carter, A. Mason, S. Burgess, S. Larsson   +6 more
semanticscholar   +1 more source

Associations between maternal thyroid function in pregnancy and child neurodevelopmental outcomes at 20 months in the Seychelles Child Development Study, Nutrition Cohort 2 (SCDS NC2)

Journal of Nutritional Science, 2021
Maternal thyroid hormones facilitate optimal foetal neurodevelopment; however, the exact role of the thyroid hormones on specific cognitive outcomes is unknown.
Anna M. Monaghan, Maria S. Mulhern, Emeir M. Mc Sorley, J.J. Strain, Theresa Winter, Edwin van Wijngaarden, Gary J. Myers, Philip W. Davidson, Conrad Shamlaye, Jude Gedeon, Alison J. Yeates   +10 more
doaj   +1 more source

NFE2-Related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland [PDF]

, 2018
Background: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend itself against excessive oxidation ...
Amendola, Elena, Bongiovanni, Massimo, Carrasco, Nancy, Chartoumpekis, Dionysios V, Habeos, Ioannis, Juvenal, Guillermo Juan, Kensler, Thomas W., Liao, Xiao-Hui, Ntalampyra, Eleni, Refetoff, Samuel, Renaud, Cédric O., Ris Stalpers, Carrie, Rossich, Luciano Esteban, Santisteban, Pilar, Somm, Emmanuel, Sykiotis, Gerasimos P., Thomasz, Lisa, Trougakos, Ioannis P, Yamamoto, Masayuki, Ziros, Panos G   +19 more
core   +1 more source

Thyroid dysfunction is associated with the loss of hepatitis B surface antigen in patients with chronic hepatitis B undergoing treatment with α-interferon

Journal of International Medical Research, 2021
Objective To investigate the influence of thyroid dysfunction on the antiviral efficacy of α-interferon in adult patients with chronic hepatitis B (CHB).
Wenfan Luo, Shuai Wu, Hongjie Chen, Yin Wu, Jie Peng   +4 more
doaj   +1 more source

EGF and TGF-β1 effects on thyroid function [PDF]

, 2011
Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as
Gabriella Mincione, Maria Carmela Di Marcantonio, Chiara Tarantelli, D'INZEO, SONIA, NICOLUSSI, Arianna, NARDI, Francesco, Caterina Francesca Donini, COPPA, Anna   +7 more
core   +2 more sources

Thyroglobulin as an evolving biomarker of iodine reserve in thyroid dysfunction assessment in pregnancy

Nigerian Journal of Medicine, 2022
Background: Despite the use of routine thyroid function tests, thyroid dysfunction is often missed in pregnant women, who may have fluctuating iodine reserves and this may be associated with an increased risk of adverse maternal and fetal outcomes due to
Terry Terfa Gbaa
doaj   +1 more source

Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.

Journal of the American Medical Association (JAMA), 2019
Importance Maternal hypothyroidism and hyperthyroidism are risk factors for preterm birth. Milder thyroid function test abnormalities and thyroid autoimmunity are more prevalent, but it remains controversial if these are associated with preterm birth ...
T. Korevaar, A. Derakhshan, P. Taylor, Marcel E. Meima, Liangmiao Chen, S. Bliddal, D. Carty, M. Meems, B. Vaidya, B. Shields, F. Ghafoor, P. Popova, L. Mosso, E. Oken, E. Suvanto, A. Hisada, J. Yoshinaga, S. Brown, J. Bassols, J. Auvinen, W. Bramer, A. López‑Bermejo, C. Dayan, Laura Boucai, M. Vafeiadi, E. Grineva, A. Tkachuck, V. Pop, T. Vrijkotte, M. Guxens, L. Chatzi, J. Sunyer, Ana Jiménez‐Zabala, I. Riano, M. Murcia, Xuemian Lu, S. Mukhtar, C. Delles, U. Feldt-Rasmussen, S. Nelson, E. Alexander, L. Chaker, Tuija Männistö, J. Walsh, E. Pearce, E. Steegers, R. Peeters   +46 more
semanticscholar   +1 more source