Results 61 to 70 of about 12,755,878 (352)

Thyroid function, intelligence, and low-moderate fluoride exposure among Chinese school-age children.

Environment International, 2019
BACKGROUND Thyroid hormones (THs) are critical for brain development. Whether low-moderate fluoride exposure affects thyroid function and what the impact is on children's intelligence remain elusive.
Mengwei Wang, Ling Liu, Huijun Li, Yonggang Li, Hongliang Liu, C. Hou, Q. Zeng, Pei-Yuan Li, Qian Zhao, Lixin Dong, Guoyu Zhou, Xingchen Yu, Li Liu, Qing Guan, Shun Zhang, Ai-guo Wang   +15 more
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The function of the thyroid gland in patients with multi-drug resistant tuberculosis

Antimicrobial Resistance and Infection Control, 2017
Background Multidrug-resistant tuberculosis (MDRTB) remains a health problem for many countries in the world. The share of MDRTB is 10–30% among newly diagnosed cases and 20–70% among relapses and treatment failure.
S. L. Matveyeva, O. S. Shevchenko, O. O. Pogorelova   +2 more
doaj   +1 more source

Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy

JAMA Network Open, 2019
Key Points Question Is exposure to ambient air pollution in the first trimester associated with thyroid function throughout pregnancy? Findings Among 9931 pregnant women in 4 European cohorts and 1 US cohort, an increase of 5 μg/m3 in exposure to ...
A. Ghassabian, Livia Pierotti, M. Basterrechea, L. Chatzi, M. Estarlich, A. Fernández-Somoano, A. Fleisch, D. Gold, J. Júlvez, P. Karakosta, A. Lertxundi, M. Lopez-Espinosa, Tessa A M Mulder, T. Korevaar, E. Oken, R. Peeters, S. Rifas-Shiman, E. Stephanou, A. Tardón, H. Tiemeier, M. Vrijheid, T. Vrijkotte, J. Sunyer, M. Guxens   +23 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Effects of Antihypertensive Drugs on Thyroid Function in Type 2 Diabetes Patients With Euthyroidism

Frontiers in Pharmacology, 2022
Objective: There is little literature about whether antihypertensive drugs would affect thyroid function in patients with euthyroid type 2 diabetes, which was significant in maintaining a proper balance of thyroid function.
Lijuan Yang, Xiuqin Sun, Yi Zhao, Hong Tao   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Interferences With Thyroid Function Immunoassays: Clinical Implications and Detection Algorithm

Endocrine reviews, 2018
Automated immunoassays used to evaluate thyroid function are vulnerable to different types of interference that can affect clinical decisions. This review provides a detailed overview of the six main types of interference known to affect measurements of ...
J. Favresse, M. Burlacu, D. Maiter, D. Gruson   +3 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stable thyroid function despite regular use of povidone-iodine throat spray for SARS-CoV-2 prophylaxis

Annals of Medicine, 2022
Background It is unclear whether unintentional ingestion of povidone-iodine following its application to the oropharyngeal space could affect thyroid function.Objective To examine thyroid function among individuals who regularly apply povidone-iodine ...
Amy May Lin Quek, Mei Yen Ng, Ooiean Teng, Nicole-Ann Lim, Geelyn Jeng Lin Ng, Samantha Peiling Yang, Mikael Hartman, Paul Anantharajah Tambyah, Alex R. Cook, Raymond Chee Seong Seet   +9 more
doaj   +1 more source