Results 101 to 110 of about 239,234 (339)

Congenital Hypothyroidism; is There any Familial Component?

open access: yesمجله دانشکده پزشکی اصفهان, 2009
Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study
Nasibeh Hasani   +11 more
doaj  

Relation between Thyroid Function Tests and Body Mass Index among Thyroid Dysfunction Patients

open access: yesUHD Journal of Science and Technology
Background: Obesity has the potential to impact thyroid function through various pathways, even in individuals considered euthyroid. The relationship between thyroid function and body mass index (BMI) remains a subject of ongoing debate.
Sanaa Othman Karim   +6 more
doaj   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

open access: yesAdvanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li   +18 more
wiley   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

Thyroid Hormones and Interference in Thyroid Function Tests: A Review

open access: yesJournal of Applied Sciences and Environmental Management
The objective of this paper was to provide a critical and concise review on thyroid hormones and what constitutes interference in thyroid function tests using appropriate Online resources.Thethyroid function tests, play a valuable and significant role ...
O. O. Edet   +4 more
doaj  

Urinary phthalate and thyroid function tests in Hashimoto’s thyroiditis

open access: yesThe Egyptian Journal of Internal Medicine
Background Although Hashimoto’s thyroiditis was recognized over a century ago, its precise cause is still unclear. There are raised concerns that plasticizers like phthalate are related to exacerbation of HT.
Salah Hussien Elhalwany   +5 more
doaj   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard   +8 more
wiley   +1 more source

Pitfalls in interpreting thyroid function tests: antibodies causing assay interferences

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2015
Many factors can compromise results of thyroid function tests, leading to possible misinterpretation and misdiagnosis. Presence of antibodies in the human serum can react with the immunoglobulins included in the assay components and cause anomalous ...
S. Pathmanathan   +2 more
doaj   +1 more source

Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study. [PDF]

open access: yes, 2016
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown.
Adli, M   +9 more
core  

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