Results 61 to 70 of about 308,721 (358)

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits

Advanced Science, EarlyView.
Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa, Fernanda S. Rasquel‐Oliveira, Brett McKinnon, Marcela Haro, Sugarniya Subramaniam, Pak Yu, Simon Coetzee, Michael S. Anglesio, Kelly N. Wright, Raanan Meyer, Anne E. Porter, Caroline E. Gargett, Sally Mortlock, Grant W. Montgomery, Michael S. Rogers, Kate Lawrenson   +15 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Gelsolin (GSN) as a key regulator in estrogen receptor-positive breast cancer: implications for prognosis, chemotherapy sensitivity, and immune infiltration

Discover Oncology
Background Gelsolin (GSN), a cytoskeletal regulatory protein implicated in cancer progression, remains understudied in estrogen receptor-positive breast cancer (ER + BC), particularly regarding its links to immune infiltration and drug resistance ...
Mian Lv, Huiling Wang, Guanqing Feng, Qingxiao Nong, Shouwen Tao, Yanfei Ma, Dalang Fang   +6 more
doaj   +1 more source

Thyroid anomalies with its embryological and clinical correlation

CHRISMED Journal of Health and Research, 2015
Objective: Thyroid gland is the first endocrine gland to start developing in the embryo. It is well-known for its developmental anomalies such as persistence of pyramidal lobe, thyroglossal duct, agenesis of isthmus, agenesis or hemiagenesis of thyroid ...
R Sharada, Chandni Gupta, Sneha Kalthur, Shakuntala R Pai, G B Rairam   +4 more
doaj   +1 more source

Distribution and dynamics of Tc-99m-pertechnetate uptake in the thyroid and other organs assessed by single-photon emission computed tomography in living mice [PDF]

, 2010
Background: Tc-99m pertechnetate is a well-known anion, used for clinical imaging of thyroid function. This gamma emitter is transported by the sodium iodide symporter but is not incorporated into thyroglobulin. Scintigraphy using Tc-99m pertechnetate or
Darcourt, Jacques, Defrise, Michel, Franken, Philippe R, Guglielmi, Julien, Koulibaly, Malick, Pourcher, Thierry, Vanhove, Christian   +6 more
core   +1 more source

Single‐Cell Transcriptomics Reveals ITGA2‐Mediated Metabolic Reprogramming and Immune Crosstalk in Pediatric Thyroid Carcinogenesis

Advanced Science, EarlyView.
This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan, Ning Li, Yan Sun, Lu Chen, Jun‐da Yin, Yun‐han Shan, Jia‐xing Zeng, Zhe‐cheng Li, Hai‐long Tan, Neng Tang, Shi Chang, Peng Huang   +11 more
wiley   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Risk factor analysis and prediction model construction for contralateral central lymph node metastasis in unilateral papillary thyroid carcinoma

World Journal of Surgical Oncology
Objective To investigate contralateral central lymph node metastasis (CCLNM) in patients with unilateral papillary thyroid carcinoma (UPTC). To provide a reference for clinical decision-making, a prediction model for the probability of CCLNM was ...
Jihao Qin, Xiaowen Fang, Chenxi Liang, Siyu Li, Xueyu Zeng, Hancheng Jiang, Zhu Chen, Jie-Hua Li   +7 more
doaj   +1 more source

Morphometry, topography and arterial supply of the thyroid gland in rhesus monkeys (Macaca mulatta Zimmermann, 1780) [PDF]

Brazilian Journal of Biology
The purpose of this research was to investigate the measures, topography, and vascularization of the thyroid gland in Macaca mulatta, a non-human primate. The study involved the dissection of ten male adult cadavers of Macaca mulatta.
A. V. Stocco, R. Medeiros-do-Nascimento, C. T. Messias, C. A Santos-Sousa, P. Souza-Junior, A. Pissinatti, M. Abidu-Figueiredo   +6 more
doaj   +1 more source

Efficiency of Artificial Neural Networks (Percepton Network) in the Diagnosis of Thyroid Diseases [PDF]

Al-Rafidain Journal of Computer Sciences and Mathematics, 2006
Thyroid gland software which was obtained through research is considered an effective system to diagnosed thyroid gland automatically. This is done by a built  complementary database which is flexible and easy at work with data patients concerning those ...
Suher Dawood, Laheeb Ibrahim, Nabil Kharofa   +2 more
doaj   +1 more source