Results 131 to 140 of about 175,066 (304)

Ontogenetic Pattern of Thyroid Hormone Receptor Expression in the Human Testis [PDF]

, 2000
Emmanuele A. Jannini, Anna Crescenzi, Nadia Rucci, Emiliano Screponi, Eleonora Carosa, Anna De Matteis, Enrico Macchia, Giulia d’Amati, M D’Armiento   +8 more
openalex   +1 more source

Different Forms of Hypothyroidism in Infants with Maternal Graves' Disease

Journal of the ASEAN Federation of Endocrine Societies
Infants of mothers with Graves’ disease (GD) may develop central hypothyroidism (CH) due to exposure of the foetal hypothalamic-pituitary-thyroid axis to higher-than-normal thyroid hormone concentrations, primary hypothyroidism (PH) due to ...
Alexis Anand Dass Lordudass, Jeanne Sze-Lyn Wong, Nalini Selveindran, Janet Yeow Hua Hong   +3 more
doaj   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, EarlyView.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator [PDF]

, 1995
Vandana Desai-Yajnik, Emir Hadzic, P Modlinger, Sunil Malhotra, G Gechlik, Herbert H. Samuels   +5 more
openalex   +1 more source

Influence af acute iodine incorporation on thyroid function and thyroidal iodine content [PDF]

, 1981
Habermann, J., Leisner, B., Pickardt, C. R., Scriba, Peter Christian, Witte, A.   +4 more
core   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Negative modulation of the epigenetic regulator, UHRF1, by thyroid hormone receptors suppresses liver cancer cell growth [PDF]

, 2014
Sheng‐Ming Wu, Wanli Cheng, Chia‐Jung Liao, Hsiang‐Cheng Chi, Yang‐Hsiang Lin, Yi‐Hsin Tseng, Chung‐Ying Tsai, Ching‐Ying Chen, Syuan‐Ling Lin, Wei‐Jan Chen, Yung‐Hsin Yeh, Chi‐Ying F. Huang, Ming‐Huang Chen, Yi‐Chen Yeh, Kwang‐Huei Lin   +14 more
openalex   +1 more source

CS27109, A Selective Thyroid Hormone Receptor-β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models [PDF]

, 2023
Shengjian Huang, Zhou Deng, Wei Wang, Guoqiang Liao, Yiru Zhao, Hua Zhong, Qian Zhang, Jing Liu, Xu-Hua Mao, Beizhong Chen, Desi Pan, You Zhou, Shengjian Huang, Zhou Deng, Wei Wang, Guoqiang Liao, Yiru Zhao, Hua Zhong, Qian Zhang, Jing Liu, Xu-Hua Mao, Beizhong Chen, Desi Pan, You Zhou   +23 more
openalex   +1 more source