Andrology, EarlyView.ABSTRACT Background Over time, family structures have grown more complex, diversifying adult relationships. While research has compared marital, cohabiting and living apart together relationships based on quality and health, less is known about their sexual dynamics.
Clotilde Sparano +16 more
wiley +1 more source
Efficacy and safety of Resmetirom, a selective thyroid hormone receptor-β agonist, in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD): a systematic review and meta-analysis. [PDF]
Sci RepSuvarna R, Shetty S, Pappachan JM.
europepmc +1 more source
Neoplastic Risk in Patients With Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani +4 more
wiley +1 more source
A new mechanism of thyroid hormone receptor β agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles. [PDF]
Acta Pharmacol SinSun K +7 more
europepmc +1 more source
A unique role of thyroid hormone receptor β in regulating notochord resorption during Xenopus metamorphosis. [PDF]
Gen Comp Endocrinol, 2019 Nakajima K, Tazawa I, Shi YB.
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The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis
Andrology, EarlyView.ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari +9 more
wiley +1 more source
Identification of a novel mutation in the thyroid hormone receptor β gene that causes thyroid hormone resistance syndrome: A case report. [PDF]
Mol Med Rep, 2019 Wang J, Lv H.
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Alimentary Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
RESISTANCE TO THYROID HORMONES: A NOVEL MUTATION OF THE THYROID HORMONE RECEPTOR β GENE IN AN ALGERIAN FAMILY. [PDF]
Acta Endocrinol (Buchar), 2017 Bellarbi D, Chentli F, Azzoug S.
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