Results 21 to 30 of about 71,901 (277)

Predicting major cardiac and cerebrovascular events in acute coronary syndrome patients using the thyroid hormone sensitivity index [PDF]

Frontiers in Endocrinology
Background and aimThe thyroid hormone sensitivity index provides a new perspective for investigating nuanced alterations in thyroid function in cardiovascular disorders.
Hui He, Hui He, Jun Wang, Long Xia, Tao Ye, Yan Luo, Qiang Chen, Qiao Feng, Xiufen Peng, Maoling Jiang, Hanxiong Liu, Tao Xiang, Shiqiang Xiong, Lin Cai, Lin Cai   +14 more
doaj   +2 more sources

Association between sensitivity to thyroid hormone and prognosis in septic patients: a retrospective cohort analysis [PDF]

Frontiers in Endocrinology
PurposeSepsis is associated with significant endocrine dysfunction, particularly in thyroid hormone metabolism. This study aims to investigate the association between thyroid hormone sensitivity indices and prognosis in sepsis, exploring their potential ...
Jia Wang, Jia Wang, Yingbai Wang, Yingbai Wang, Zihan Xu, Chuxun Chou, Jiaofeng Xiang, Xizhi Zhang, Xuefei Hou, Xuefei Hou, Suru Yue, Suru Yue, Shicai Ye, Feng Chen, Jiayuan Wu, Jiayuan Wu   +15 more
doaj   +2 more sources

Syndromes of Impaired Sensitivity to Thyroid Hormone

, 2016
Thyroid hormone (TH) synthesis and release is under feedback regulation by the hypothalamic input to the pituitary via thyroid-stimulating hormone (TSH) and thyroid-releasing hormone (TRH) resulting in pituitary secretion of TSH.
Refetoff, Samuel, Roy E. Weiss, Samuel Refetoff, Weiss, Roy E, Alexandra M. Dumitrescu, Dumitrescu, Alexandra M   +5 more
core   +2 more sources

High TSH levels during TSH suppression therapy in DTC postoperative patients are associated with low DIO2 expression in the thyroid and impaired thyroid hormone sensitivity [PDF]

Frontiers in Endocrinology
IntroductionSome patients with differentiated thyroid cancer (DTC) exhibit persistently elevated TSH levels despite undergoing TSH suppression therapy after total thyroidectomy. This study aims to investigate the expression of type 2 deiodinase (DIO2) in
Jialu Wu, Juan Huang, Juan Huang, Zhe Yan, Anqi Yuan, Yifei Song, Hui Huang   +6 more
doaj   +2 more sources

Reduced sensitivity to thyroid hormones is associated with differentiated thyroid cancer in the euthyroid thyroidectomy population

Frontiers in Endocrinology
BackgroundThe inconclusive associations between thyroid-related hormones and differentiated thyroid cancer (DTC) suggest complex pathophysiologic processes, for which thyroid hormone sensitivity may provide new insights.MethodsWe retrospectively analyzed
Huaijin Xu, Huaijin Xu, Hongzhou Liu, Xiaodong Hu, Xiaomeng Jia, Zhe Xue, Anning Wang, Shaoyang Kang, Shaoyang Kang, Zhaohui Lyu, Zhaohui Lyu   +10 more
doaj   +3 more sources

Elevated mitochondrial DNA copy number in euthyroid individuals with impaired peripheral sensitivity to thyroid hormones [PDF]

Frontiers in Endocrinology
BackgroundThe role of thyroid hormone sensitivity in metabolic and neoplastic diseases is well recognized, however, its association with mitochondrial DNA copy number (mtDNAcn) in euthyroid individuals remains unclear.ObjectiveThis cross-sectional study ...
Li Qin, Tingting Huang, Danmei Zhang, Guochao Li, Liqin Wei, Juan Liu   +5 more
doaj   +2 more sources

Correlation between thyroid hormone sensitivity and the risk of polycystic ovary syndrome [PDF]

BMC Endocrine Disorders
Objective There has been some confusion in earlier research on the connection between thyroid function and polycystic ovary syndrome (PCOS). This research is aimed to probe into the correlation between thyroid condition and the risk of PCOS from a new ...
Qian Wang, Ru Zhao, Chen Han, Zeyu Huang, Yan Bi, Xiaowen Zhang, Shanmei Shen   +6 more
doaj   +2 more sources

Impaired Sensitivity to Thyroid Hormone and Risk of Carotid Plaque Development in a Chinese Health Check-Up Population: A Large Sample Cross-Sectional Study

Diabetes, Metabolic Syndrome and Obesity
Jiangling Wang,1,2,* Lijuan Yang,3,* Wei Liu,1 Chaogang Wei,1 Junkang Shen1 1Department of Radiology, The Second Affiliated Hospital of Soochow University, Soochow, Jiangsu, People’s Republic of China; 2Department of Physical Diagnosis, Huadong ...
Wang J, Yang L, Liu W, Wei C, Shen J
doaj   +1 more source

Relationship between Thyroid Hormone Sensitivity Indices and Osteoporosis in Patients with Normal Thyroid Function Type 2 Diabetes Mellitus [PDF]

Zhongguo quanke yixue
Background With the increasing aging population, the prevalence of osteoporosis in patients with type 2 diabetes mellitus (T2DM) is rising year by year. It has also been found that impaired sensitivity to thyroid hormone is associated with abnormal bone ...
ZHANG Yuan, CHEN Guanhua, LYU Shanshan, JING Yali
doaj   +2 more sources

Thyroid hormone resistance: a novel mutation in thyroid hormone receptor beta (THRB) gene - case report

The Turkish Journal of Pediatrics, 2013
Thyroid hormone resistance (THR) is a dominantly inherited syndrome characterized by reduced sensitivity to thyroid hormones. It is usually caused by mutations in the thyroid hormone receptor beta (THRB) gene.
Emregül Işık, Paolo Beck Peccoz, Irene Campi, Alev Özön, Ayfer Alikaşifoğlu, Nazlı Gönç, Nurgün Kandemir   +6 more
doaj   +4 more sources