Results 81 to 90 of about 71,901 (277)

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Thyroid hormone sensitivity indices and hs-CRP as biochemical predictors of arteriovenous fistula maturation in diabetic nephropathy [PDF]

Journal of Medical Biochemistry
Background: Autogenous arteriovenous fistula (AVF) maturation is essential for successful hemodialysis in patients with diabetic nephropathy (DN). However, its outcome is often unpredictable.
Li Dan, Zhao Bing, Zou Lihong
doaj   +1 more source

Association Between Sensitivity to Thyroid Hormones and Metabolic Dysfunction-Associated Fatty Liver Disease in Euthyroid Subjects: A Cross-Sectional Study

, 2023
Huanxin Liu,1 Yuling Xing,2 Qian Nie,1 Zhong Li,3 Cuiqiao Meng,1 Huijuan Ma2,4 1Health Examination Center, Hebei General Hospital, Shijiazhuang, Hebei, 050051, People’s Republic of China; 2Department of Endocrinology, Hebei General Hospital, Shijiazhuang,
Liu H, Li Z, Meng C, Xing Y, Nie Q, Ma H
core  

DataSheet_1_Impaired Sensitivity to Thyroid Hormones Is Associated With Elevated Blood Glucose in Coronary Heart Disease.docx

, 2022
ContextThyroid hormones influence glucose homeostasis through central and peripheral regulation. To date, the association between thyroid hormone sensitivity and elevated blood glucose (EBG) in patients with coronary heart disease (CHD) remains unknown ...
Shan Gao (46743), Lu Yu (74016), Guangwei Pan (10984209), Tong Yang (103174), Lin Li (28817), Qiang Xu (71522), Yanchao Zheng (10839815), Mei Ma (2271595), Jinyu Su (12809764), Chunquan Yu (6569021), Rongrong Yang (477537), Yijia Liu (348194), Yang Wang (5921), Fanfan Liu (1518379), Qi Cheng (46307), Zhu Li (193162), Yuanyuan He (505528)   +16 more
core   +1 more source

Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging

Aging, 2019
An inverse correlation between thyroid hormone levels and longevity has been reported in several species and reduced thyroid hormone levels have been proposed as a biomarker for healthy aging and metabolic fitness. However, hypothyroidism is a medical condition associated with compromised health and reduced life expectancy.
Lopez-Noriega, L, Capilla-Gonzalez, V, Cobo-Vuilleumier, N, Martin-Vazquez, E, Isabel Lorenzo, P, Martinez-Force, E, Soriano-Navarro, M, Garcia-Fernandez, M, Yanina Romero-Zerbo, S, Javier Bermudez-Silva, F, Diaz-Contreras, I, Sanchez-Cuesta, A, Santos-Ocana, C, Hmadcha, A, Soria, B, Martin, F, Raymond Gauthier, B, Martin-Montalvo, A   +17 more
openaire   +11 more sources

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Coexistence of Autoimmune Hyper-and Hypothyroidism in a Kindred with Reduced Sensitivity to Thyroid Hormone

, 2020
International audienceIntroduction: Resistance to thyroid hormone beta (RTHβ) is a rare disease with an autosomal dominant transmission. Diagnosis may be challenging especially in patients with hyper-or hypothyroidism.
Abdellaoui, Yasmine, Cazabat, Laure, Magkou, Dimitra, Bakopoulou, Sofia, Zaharia, Ramona, Raffin-Sanson, Marie Laure   +5 more
core   +1 more source

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source

Changes of central sensitivity to thyroid hormones during pregnancy

Endocrine Abstracts
Introduction/Aim: Central sensitivity to thyroid hormones refers to the sensitivity of the hypothalamic-pituitary-thyroid (HPT) axis to changes in circulating free thyroxine (fT4). The relationship between fT4 levels and iodine intake is complex. The aim of the present study was to assess central sensitivity to thyroid hormones in pregnancy against ...
Ioannis Ilias, Charalampos Milionis, Maria Alexiou, Ekaterini Michou, Chrysi Karavasili, Evangelia Venaki, Kostas Markou, Irene Mamali, Eftychia Koukkou   +8 more
openaire   +1 more source