Results 101 to 110 of about 449,550 (308)

Can increased prenatal exposure to thyroid hormones alter physiology and behaviour in the long-term? Insights from an experimental study in Japanese quails [PDF]

PeerJ
Maternal thyroid hormones (triiodothyronine T3 and thyroxine T4) are important regulators of embryonic development and gene expression. In chickens, prenatal thyroid hormone treatment has been shown to influence embryonic gene expression and postnatal ...
Kalle Aho, Antoine Stier, Tom Sarraude, Bin-Yan Hsu, Suvi Ruuskanen   +4 more
doaj   +2 more sources

Demonstration of reciprocal diurnal variation in human serum T3 and rT3 concentration demonstrated by mass spectrometric analysis and establishment of thyroid hormone reference intervals

Therapeutic Advances in Endocrinology and Metabolism, 2020
Background: There has been a wide range of reference intervals proposed in previous literature for thyroid hormones due to large between-assay variability of immunoassays, as well as lack of correction for collection time.
Qian Sun, Lívia Avallone, Brian Stolze, Katherine A. Araque, Yesim Özarda, Jacqueline Jonklaas, Toral Parikh, Kerry Welsh, Likhona Masika, Steven J. Soldin   +9 more
doaj   +1 more source

Why do national IDD control programmes fail : case studies from Indo-China

, 2014
Iodine is a trace element and is responsible for the synthesis of thyroid hormones that are critical for brain development especially in the foetal and early childhood development1.
Ma, Gary (R17095)
core  

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

Advanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji, Yan Fang, Shen Zhang, Weichen Xu, Wenyun Guo, Jing Chen, Mingrui Zhu, Congjian Wen, Siming Chen, Yuli Zhu, Huixiong Xu, Haohao Yin   +11 more
wiley   +1 more source

Thyroid hormones and neurological impairments during the first two days after stroke: A pilot study

Heliyon
Despite plenty of studies on the change in thyroid hormones after stroke, there is still no consensus for a comprehensive conclusion and clinical application.
Kobra Akhoundzadeh, Ashraf Zarvani, Fatemeh Mohajerani, Sakineh Shafia   +3 more
doaj   +1 more source

VCP‐Regulated LMF2 Stabilizes the Cholesterol Biosynthesis Enzyme HMGCS1 to Drive Cancer Progression and Confer Capecitabine Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
LMF2 drives progression and capecitabine resistance in triple‐negative breast cancer (TNBC). Mechanistically, VCP prevents NBR1‐mediated autophagic degradation of LMF2, thereby stabilizing it. Stabilized LMF2 subsequently suppresses NDP52‐mediated autophagic degradation of HMGCS1, a rate‐limiting cholesterol biosynthesis enzyme.
Qian Zhao, Lisa Andriani, Yin‐Ling Zhang, Shao‐Ying Yang, Yun‐Xiao Ling, Min‐Ying Huang, Jia‐Yang Cai, Fang‐Lin Zhang, Xin Hu, A‐Yong Cao, Zhi‐Min Shao, Guang‐Yu Liu, Da‐Qiang Li   +12 more
wiley   +1 more source

Thyroid hormones and fetal brain development

, 2005
Thyroid hormones are intricately involved in the developing fetal brain. The fetal central nervous system is sensitive to the maternal thyroid status. Critical amounts of maternal T3 and T4 must be transported across the placenta to the fetus to ensure ...
Franklyn, Jayne, Kilby, Mark, Pemberton, Helen   +2 more
core   +3 more sources

Associations between rCBFs and thyroid hormones in the MCI group.

, 2019
Associations between rCBFs and thyroid hormones in the MCI group.
Shohei Nomoto (6551420), Yukiko Mori (805957), Satomi Kubota (5206322), Takahiko Yoshimoto (2830304), Akinori Futamura (6082784), Hirotaka Ochiai (6551426), Azusa Sugimoto (6551429), Kenjiro Ono (419133), Hidetomo Murakami (6105284), Akira Minoura (6551435), Satoshi Yano (6105302), Takako Shirasawa (6551432), Akatsuki Kokaze (6551438), Takeshi Kuroda (2455990), Ryuta Kinno (6551423)   +14 more
core   +1 more source

Abnormal serum thyroid hormones concentration with healthy functional gland: A review on the metabolic role of thyroid hormones transporter proteins [PDF]

, 2011
Laboratory findings can definitely help the patients not to enter into status, where the damage might be happen due to a miss-diagnosis based on clinical assessment alone.
Mansourian, A.R.
core   +1 more source

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source