Results 81 to 90 of about 420,840 (296)

Behavioral assessment of children and adolescents with Graves' disease: A prospective study.

PLoS ONE, 2021
Previous studies have identified frequent comorbid neuropsychiatric disorders and conditions in adults with thyrotoxicosis. These studies are scarce or even lacking in pediatric population.
Sherifa Ahmed Hamed, Fadia Ahmed Attiah, Samir Kamal Abdulhamid, Mohamed Fawzy   +3 more
doaj   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Revisiting thyroid hormones in schizophrenia [PDF]

, 2012
Thyroid hormones are crucial during development and in the adult brain. Of interest, fluctuations in the levels of thyroid hormones at various times during development and throughout life can impact on psychiatric disease manifestation and response to ...
Ruano, D, Azevedo, MH, Pereira, AT, Santos, NC, Palha, JA, Costa, P, Soares, MJ, MacEdo, A, Valente, J   +8 more
core   +2 more sources

Changes in Central Sensitivity to Thyroid Hormones vs. Urine Iodine during Pregnancy

Medical Sciences
Introduction/Aim: Central sensitivity to thyroid hormones refers to the responsiveness of the hypothalamic–pituitary–thyroid (HPT) axis to changes in circulating free thyroxine (fT4).
Ioannis Ilias, Charalampos Milionis, Maria Alexiou, Ekaterini Michou, Chrysi Karavasili, Evangelia Venaki, Kostas Markou, Irini Mamali, Eftychia Koukkou   +8 more
doaj   +1 more source

Impaired Sensitivity to Thyroid Hormones is Associated with Mild Cognitive Impairment in Euthyroid Patients with Type 2 Diabetes

, 2023
Zi-Wei Yu,1,* Sheng-Dan Pu,2,* Xiao-Tong Sun,2 Xi-Chang Wang,1 Xin-Yuan Gao,2 Zhong-Yan Shan1 1Department of Endocrinology and Metabolism and the Institute of Endocrinology, The NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases ...
Pu SD, Sun XT, Wang XC, Yu ZW, Shan ZY, Gao XY   +5 more
core  

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

The impact of thyroid hormone dysfunction on ischemic heart disease

Endocrine Connections, 2019
Thyroid hormones have a central role in cardiovascular homeostasis. In myocardium, these hormones stimulate both diastolic myocardial relaxation and systolic myocardial contraction, have a pro-angiogenic effect and an important role in extracellular ...
Madalena von Hafe, João Sergio Neves, Catarina Vale, Marta Borges-Canha, Adelino Leite-Moreira   +4 more
doaj   +1 more source

Psychological well-being on thyroid hormone replacement [PDF]

Despite 100 years after the discovery of thyroxine, controversy still exists regarding optimal thyroid hormone replacement therapy. Several anecdotal reports suggest that thyroxine alone therapy does not normalise psychological wellbeing.
Saravanan, Ponnusamy
core  

Immunohistochemistry differentiates papillary thyroid carcinoma arising in ectopic thyroid tissue from secondary lymph node metastases.

, 2007
Objective: To verify whether immunohistochemistry might be useful in the distinction between a true laterocervical metastasis of an undetected thyroid carcinoma and a primary tumor outside the gland.
ARAGONA, Federico, CACCIATORE M, THYROID JUL, CABIBI, Daniela, GUARNOTTA, Carla   +4 more
core   +1 more source

Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer [PDF]

, 2009
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the publication of the American Thyroid Association's guidelines for the management of these disorders was published in
Steward DL, Tuttle RM, Schlumberger M, Martin Schlumberger, Stephanie L. Lee, Haugen, Bryan R., McIver B, Cooper, David S., Haugen BR, Cooper DS, American Thyroid Association Guidelines Taskforce on Thyroid Nodules, Mandel, Susan J., Steward, David L., Bryan McIver, Richard T. Kloos, Mazzaferri EL, Steven I. Sherman, Doherty, Gerard M., Sherman, Steven I., Susan J. Mandel, Lee SL, Kloos RT, R. Michael Tuttle, McIver, Bryan, Ernest L. Mazzaferri, Kloos, Richard T., Lee, Stephanie L., Gerard M. Doherty, Pacini, Furio, Doherty GM, Bryan R. Haugen, Schlumberger, Martin, Furio Pacini, Differentiated Thyroid Cancer, David S. Cooper, Mazzaferri, Ernest L., Mandel SJ, Sherman SI, David L. Steward, Tuttle, R. Michael   +39 more
core   +1 more source