Results 21 to 30 of about 119,841 (316)

Associations between maternal thyroid function in pregnancy and child neurodevelopmental outcomes at 20 months in the Seychelles Child Development Study, Nutrition Cohort 2 (SCDS NC2)

Journal of Nutritional Science, 2021
Maternal thyroid hormones facilitate optimal foetal neurodevelopment; however, the exact role of the thyroid hormones on specific cognitive outcomes is unknown.
Anna M. Monaghan, Maria S. Mulhern, Emeir M. Mc Sorley, J.J. Strain, Theresa Winter, Edwin van Wijngaarden, Gary J. Myers, Philip W. Davidson, Conrad Shamlaye, Jude Gedeon, Alison J. Yeates   +10 more
doaj   +1 more source

Thyroid Hormones and Their Role in Male Infertility: A Comprehensive Review [PDF]

International Journal of Biomedicine
Thyroid hormones are pivotal regulators of various physiological processes, including reproductive function. While the impact of thyroid dysfunction on female fertility has been extensively studied, its association with male infertility has gained ...
Ramadan S. Hussein
doaj   +1 more source

Main Factors Involved in Thyroid Hormone Action

Molecules, 2021
The thyroid hormone receptors are the mediators of a multitude of actions by the thyroid hormones in cells. Most thyroid hormone activities require interaction with nuclear receptors to bind DNA and regulate the expression of target genes. In addition to
Lorena Tedeschi, Cristina Vassalle, Giorgio Iervasi, Laura Sabatino   +3 more
doaj   +1 more source

Treatment With Thyroid Hormone [PDF]

Endocrine Reviews, 2014
Thyroid hormone deficiency can have important repercussions. Treatment with thyroid hormone in replacement doses is essential in patients with hypothyroidism. In this review, we critically discuss the thyroid hormone formulations that are available and approaches to correct replacement therapy with thyroid hormone in primary and central hypothyroidism ...
BIONDI, BERNADETTE, Wartofsky L.
openaire   +3 more sources

Imbalance between thyroid hormones and the dopaminergic system might be central to the pathophysiology of restless legs syndrome: a hypothesis

Clinics, 2010
Data collected from medical literature indicate that dopaminergic agonists alleviate Restless Legs Syndrome symptoms while dopaminergic agonists antagonists aggravate them. Dopaminergic agonists is a physiological regulator of thyroid-stimulating hormone.
Jose Carlos Pereira Jr., Marcia Pradella-Hallinan, Hugo de Lins Pessoa   +2 more
doaj   +1 more source

Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3

Frontiers in Cell and Developmental Biology, 2021
Interaction between thyroid hormones and the immune system is reported in the literature. Thyroid hormones, thyroxine, T4, but also T3, act non-genomically through mechanisms that involve a plasma membrane receptor αvβ3 integrin, a co-receptor for ...
Elena Candelotti, Roberto De Luca, Roberto Megna, Mariangela Maiolo, Paolo De Vito, Fabio Gionfra, Zulema Antonia Percario, Monica Borgatti, Roberto Gambari, Paul J. Davis, Paul J. Davis, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Fabio Polticelli, Tiziana Persichini, Marco Colasanti, Elisabetta Affabris, Jens Z. Pedersen, Sandra Incerpi   +21 more
doaj   +1 more source

Thyroid gland: physiology and pathology (a short review)

Academic Science Journal
 One of the main parts of the endocrine system is the thyroid gland, it produces thyroid hormones, tetraiodothyronine, and triiodothyronine, which are important for metabolic health. In this article, we review the most important thyroid hormones and the
Fatimah AL- Mahdawi, Mazin Mohammed, Mustafa Taher, Al-Mahdawi ,A. S. Muthanna, Nameer Fadhil alkalifa, Ammar Kadi, Irina Potoroko, Marouane Chemek   +7 more
doaj   +1 more source

Influence of Thyroid Hormones on the Body’s Adaptive Capabilities (Review)

Журнал медико-биологических исследований
Thyroid hormones take an active part in the regulation of many body reactions, including adaptive responses. The purpose of this review was to analyse the role of thyroid hormones in the adaptive response of the body to stress factors.
Yuliya A. Shatyr, Galina A. Sroslova, Ruslan I. Glushakov   +2 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source