Results 11 to 20 of about 90,983 (266)
Therapeutic Advances in Endocrinology and Metabolism, 2020 Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome with high mortality for which there is no proven therapy to improve its prognosis.
João Sérgio Neves +9 more
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Thyroid hormone receptors and resistance to thyroid hormone disorders [PDF]
Nature Reviews Endocrinology, 2014 Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs), which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor β (THRB) genes. Patients with mutations in THRB present with resistance to thyroid hormone β (RTHβ), which is a disorder characterized by elevated levels of thyroid hormone, normal
Tânia M, Ortiga-Carvalho +2 more
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Dynamics of thyroid diseases and thyroid‐axis gland masses
Molecular Systems Biology, 2022 Thyroid disorders are common and often require lifelong hormone replacement. Treating thyroid disorders involves a fascinating and troublesome delay, in which it takes many weeks for serum thyroid‐stimulating hormone (TSH) concentration to normalize ...
Yael Korem Kohanim +8 more
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Frontiers in Molecular Neuroscience, 2022 Thyroid hormones clearly play a role in the seasonal regulation of reproduction, but any role they might play in song behavior and the associated seasonal neuroplasticity in songbirds remains to be elucidated.
Jasmien E. M. J. Orije +12 more
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Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]
Endocrine-Related Cancer, 2013 Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
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Therapy with L-thyroxine and Omnadren after Cardiac Surgery. A Case Report [PDF]
Folia Medica, 2019 Background: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid ...
Georgi J. Stoitsev +6 more
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Intranasal delivery of Thyroid hormones in MCT8 deficiency.
PLoS ONE, 2020 Loss of function mutations in the gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to severe neurodevelopmental defects in humans associated with a specific thyroid hormone phenotype manifesting high serum 3,5,3 ...
Carmen Grijota-Martínez +5 more
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Thyroid Hormones and Cancer: A Comprehensive Review of Preclinical and Clinical Studies
Frontiers in Endocrinology, 2019 Thyroid hormones take major part in normal growth, development and metabolism. Over a century of research has supported a relationship between thyroid hormones and the pathophysiology of various cancer types.
Eilon Krashin +7 more
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Role of maternal thyroid hormones in the developing neocortex and during human evolution
Frontiers in Neuroanatomy, 2013 The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
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Thyroid hormone sensitivity and diabetes onset: a longitudinal cross-lagged cohort
Frontiers in Endocrinology, 2023 PurposeThyroid hormones sensitivity is a newly proposed clinical entity closely related with metabolic health. Prior studies have reported the cross-sectional relationship between thyroid hormones sensitivity and diabetes; however, the longitudinal ...
Cancan Cui +8 more
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