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Archives of Epilepsy, 2018 The nervous and endocrine systems are 2 important related systems. Thyroid hormones, in particular, bind to the nuclear receptors of neuronal and glial cells, which affects migration, myelination, and synaptogenesis, and contributes to the development ...
Sibel GÜLDİKEN
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Poisoning with Thyroid Hormones Used Illegally—Systematic Review [PDF]
PharmaceuticalsBackground/Objectives: Thyroid hormones, considered safe in therapeutic doses, are used to treat hypothyroidism, a common condition. Due to a combination of factors, including their mechanism of action, availability, and low price, these drugs are used ...
Monika Skrzypiec-Spring +7 more
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Longitudinal evidence of the impact of normal thyroid stimulating hormone variations on cognitive functioning in very old age [PDF]
, 2008 The purpose of this study was to examine longitudinal associations among thyroid stimulating hormone (TSH) levels and cognitive performance. Data collected at the first three assessment times, approximately 3 years apart, are reported for the survivors ...
Wahlin, TBR, Wahlin, A, Bunce, D
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Endocrine Regulation on Bone by Thyroid
Frontiers in Endocrinology, 2022 BackgroundAs an endocrine organ, the thyroid acts on the entire body by secreting a series of hormones, and bone is one of the main target organs of the thyroid.SummaryThis review highlights the roles of thyroid hormones and thyroid diseases in bone ...
Siyuan Zhu +7 more
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Thyroid Hormone Transporters [PDF]
Biochemical Society Transactions, 2005 Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Friesema, Edith +3 more
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Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
Fluids and Barriers of the CNS, 2023 Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood–brain barrier (BBB), and in neural cells, being the ...
Marina Guillén-Yunta +6 more
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Treatment With Thyroid Hormone [PDF]
Endocrine Reviews, 2014 Thyroid hormone deficiency can have important repercussions. Treatment with thyroid hormone in replacement doses is essential in patients with hypothyroidism. In this review, we critically discuss the thyroid hormone formulations that are available and approaches to correct replacement therapy with thyroid hormone in primary and central hypothyroidism ...
BIONDI, BERNADETTE, Wartofsky L.
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Frontiers in Endocrinology, 2023 A comprehensive review was conducted to compile the contributions of Mary B. Dratman and studies by other researchers in the field of nongenomic actions of thyroid hormones in adult mammalian brain.
Nilkanta Chakrabarti +4 more
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Frontiers in Psychiatry, 2021 Abnormal thyroid function in major depressive disorder (MDD) has been studied extensively, but the results still remain inconsistent. In China, few large-scale studies have investigated the differences in the levels of thyroid hormones between patients ...
Yanan Zhou +11 more
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New Approaches to Thyroid Hormones and Purinergic Signaling [PDF]
, 2013 It is known that thyroid hormones influence a wide variety of events at the molecular, cellular, and functional levels. Thyroid hormones (TH) play pivotal roles in growth, cell proliferation, differentiation, apoptosis, development, and metabolic ...
Andréia Buffon +5 more
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