Results 11 to 20 of about 106,374 (310)
Intranasal delivery of Thyroid hormones in MCT8 deficiency. [PDF]
PLoS ONE, 2020 Loss of function mutations in the gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to severe neurodevelopmental defects in humans associated with a specific thyroid hormone phenotype manifesting high serum 3,5,3 ...
Carmen Grijota-Martínez +5 more
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Archives of Epilepsy, 2018 The nervous and endocrine systems are 2 important related systems. Thyroid hormones, in particular, bind to the nuclear receptors of neuronal and glial cells, which affects migration, myelination, and synaptogenesis, and contributes to the development ...
Sibel GÜLDİKEN
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Thyroid Hormones and Mitochondria
Bioscience Reports, 2002 Because of their central role in the regulation of energy-transduction, mitochondria, the major site of oxidative processes within the cell, are considered a likely subcellular target for the action that thyroid hormones exert on energy metabolism. However, the mechanism underlying the regulation of basal metabolic rate (BMR) by thyroid hormones still ...
GOGLIA F., SILVESTRI E., LANNI, Antonia
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Hyperthyroidism and Wnt Signaling Pathway: Influence on Bone Remodeling
Metabolites, 2023 Graves’ disease is an autoimmune disease of the thyroid gland, characterized by increased production of thyroid hormones, which can affect many different organ systems in the body.
Dunja Mudri +4 more
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Therapeutic Advances in Endocrinology and Metabolism, 2020 Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome with high mortality for which there is no proven therapy to improve its prognosis.
João Sérgio Neves +9 more
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Thyroid hormone receptors and resistance to thyroid hormone disorders [PDF]
Nature Reviews Endocrinology, 2014 Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs), which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor β (THRB) genes. Patients with mutations in THRB present with resistance to thyroid hormone β (RTHβ), which is a disorder characterized by elevated levels of thyroid hormone, normal
Tânia M, Ortiga-Carvalho +2 more
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Dynamics of thyroid diseases and thyroid‐axis gland masses
Molecular Systems Biology, 2022 Thyroid disorders are common and often require lifelong hormone replacement. Treating thyroid disorders involves a fascinating and troublesome delay, in which it takes many weeks for serum thyroid‐stimulating hormone (TSH) concentration to normalize ...
Yael Korem Kohanim +8 more
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Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]
Endocrine-Related Cancer, 2013 Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
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Therapy with L-thyroxine and Omnadren after Cardiac Surgery. A Case Report [PDF]
Folia Medica, 2019 Background: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid ...
Georgi J. Stoitsev +6 more
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Frontiers in Molecular Neuroscience, 2022 Thyroid hormones clearly play a role in the seasonal regulation of reproduction, but any role they might play in song behavior and the associated seasonal neuroplasticity in songbirds remains to be elucidated.
Jasmien E. M. J. Orije +12 more
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