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Analytical Science Advances, 2023 Measurement of hormones is important for the diagnosis and management of endocrine diseases. The thyroid hormones thyroxine (T4) and triiodothyronine (T3) are among the most commonly measured hormones in clinical laboratories, and it is the concentration
Alexander B. Westbye +4 more
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Hyperthyroidism and Wnt Signaling Pathway: Influence on Bone Remodeling
Metabolites, 2023 Graves’ disease is an autoimmune disease of the thyroid gland, characterized by increased production of thyroid hormones, which can affect many different organ systems in the body.
Dunja Mudri +4 more
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Therapeutic Advances in Endocrinology and Metabolism, 2020 Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome with high mortality for which there is no proven therapy to improve its prognosis.
João Sérgio Neves +9 more
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Dynamics of thyroid diseases and thyroid‐axis gland masses
Molecular Systems Biology, 2022 Thyroid disorders are common and often require lifelong hormone replacement. Treating thyroid disorders involves a fascinating and troublesome delay, in which it takes many weeks for serum thyroid‐stimulating hormone (TSH) concentration to normalize ...
Yael Korem Kohanim +8 more
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Thyroid hormone receptors and resistance to thyroid hormone disorders [PDF]
Nature Reviews Endocrinology, 2014 Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs), which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor β (THRB) genes. Patients with mutations in THRB present with resistance to thyroid hormone β (RTHβ), which is a disorder characterized by elevated levels of thyroid hormone, normal
Tânia M, Ortiga-Carvalho +2 more
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Therapy with L-thyroxine and Omnadren after Cardiac Surgery. A Case Report [PDF]
Folia Medica, 2019 Background: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid ...
Georgi J. Stoitsev +6 more
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Frontiers in Molecular Neuroscience, 2022 Thyroid hormones clearly play a role in the seasonal regulation of reproduction, but any role they might play in song behavior and the associated seasonal neuroplasticity in songbirds remains to be elucidated.
Jasmien E. M. J. Orije +12 more
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Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]
Endocrine-Related Cancer, 2013 Abstract Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
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Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]
, 2008 The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Brand, H., van den +5 more
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Intranasal delivery of Thyroid hormones in MCT8 deficiency.
PLoS ONE, 2020 Loss of function mutations in the gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to severe neurodevelopmental defects in humans associated with a specific thyroid hormone phenotype manifesting high serum 3,5,3 ...
Carmen Grijota-Martínez +5 more
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