Results 31 to 40 of about 420,840 (296)

Thyroid Hormones and Cancer: A Comprehensive Review of Preclinical and Clinical Studies

Frontiers in Endocrinology, 2019
Thyroid hormones take major part in normal growth, development and metabolism. Over a century of research has supported a relationship between thyroid hormones and the pathophysiology of various cancer types.
Eilon Krashin, Eilon Krashin, Agnieszka Piekiełko-Witkowska, Martin Ellis, Martin Ellis, Martin Ellis, Osnat Ashur-Fabian, Osnat Ashur-Fabian   +7 more
doaj   +1 more source

Role of maternal thyroid hormones in the developing neocortex and during human evolution

Frontiers in Neuroanatomy, 2013
The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
doaj   +1 more source

Thyroid hormone sensitivity and diabetes onset: a longitudinal cross-lagged cohort

Frontiers in Endocrinology, 2023
PurposeThyroid hormones sensitivity is a newly proposed clinical entity closely related with metabolic health. Prior studies have reported the cross-sectional relationship between thyroid hormones sensitivity and diabetes; however, the longitudinal ...
Cancan Cui, He Sui, Zhijia Wang, Te Zhang, Jia Zheng, Han Yan, Qianyu Li, Zhanhao Mo, Lin Liu   +8 more
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Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Bergman, A., Berg, J.J.J., van den, van den Berg, J.H.J., Meerts, I.A.T.M., Weijers, B.M., van den Berg, J.J.J., Brouwer, A., Assink, Y., Cenijn, P.H., Berg, J.H.J. van den, Koeman, J.H., Assin, Y.   +11 more
core   +2 more sources

Associations between maternal thyroid function in pregnancy and child neurodevelopmental outcomes at 20 months in the Seychelles Child Development Study, Nutrition Cohort 2 (SCDS NC2)

Journal of Nutritional Science, 2021
Maternal thyroid hormones facilitate optimal foetal neurodevelopment; however, the exact role of the thyroid hormones on specific cognitive outcomes is unknown.
Anna M. Monaghan, Maria S. Mulhern, Emeir M. Mc Sorley, J.J. Strain, Theresa Winter, Edwin van Wijngaarden, Gary J. Myers, Philip W. Davidson, Conrad Shamlaye, Jude Gedeon, Alison J. Yeates   +10 more
doaj   +1 more source

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Farjo, Nilofer, Haslam, Iain S., Hardman, Jonathan A., Paus, Ralf, Farjo, Bessam   +4 more
core   +5 more sources

Thyroid Hormones and Mesotherapy [PDF]

Frontiers in Endocrinology, 2011
Thyroid hormones are the master regulator of body metabolism and growth. They act at molecular level to manipulate genes and cellular functions to balance the basic metabolic rate. They bind to superfamily of nuclear receptors that recognize discrete sequences of DNA and act as transcription factors (Renkawitz et al., 1996).
openaire   +3 more sources

Main Factors Involved in Thyroid Hormone Action

Molecules, 2021
The thyroid hormone receptors are the mediators of a multitude of actions by the thyroid hormones in cells. Most thyroid hormone activities require interaction with nuclear receptors to bind DNA and regulate the expression of target genes. In addition to
Lorena Tedeschi, Cristina Vassalle, Giorgio Iervasi, Laura Sabatino   +3 more
doaj   +1 more source

Thyroid Hormones and Mitochondria

Bioscience Reports, 2002
Because of their central role in the regulation of energy-transduction, mitochondria, the major site of oxidative processes within the cell, are considered a likely subcellular target for the action that thyroid hormones exert on energy metabolism. However, the mechanism underlying the regulation of basal metabolic rate (BMR) by thyroid hormones still ...
GOGLIA F., SILVESTRI E., LANNI, Antonia
openaire   +3 more sources

Imbalance between thyroid hormones and the dopaminergic system might be central to the pathophysiology of restless legs syndrome: a hypothesis

Clinics, 2010
Data collected from medical literature indicate that dopaminergic agonists alleviate Restless Legs Syndrome symptoms while dopaminergic agonists antagonists aggravate them. Dopaminergic agonists is a physiological regulator of thyroid-stimulating hormone.
Jose Carlos Pereira Jr., Marcia Pradella-Hallinan, Hugo de Lins Pessoa   +2 more
doaj   +1 more source