Results 51 to 60 of about 420,840 (296)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Thyroid Disorders and Chronic Kidney Disease
International Journal of Nephrology, 2014 Thyroid hormones play a very important role regulating metabolism, development, protein synthesis, and influencing other hormone functions. The two main hormones produced by the thyroid are triiodothyronine (T3) and thyroxine (T4).
Mohamed Mohamedali +4 more
doaj +1 more source
Thyroid Functioning in Diabetes Mellitus Complicated with Chronic Renal Disease
Mìžnarodnij Endokrinologìčnij Žurnal, 2013 Thyroid hormones affect renal physiological development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of a number of nephron transport systems, and water-electrolyte metabolism.
Ye.G. Sazonova, T.V. Mokhort
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Thyroid dysfunction in the ageing patient
Mìžnarodnij Endokrinologìčnij ŽurnalThyroid dysfunction is a common endocrine disorder in the general population, with a reported prevalence of 10–15 %. This rate is higher in older adults, with an estimated prevalence of 25 % in some populations.
O.V. Bilookyi, V.L. Vasiuk, O.A. Shupik
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Measurement of salivary thyroid hormones using the LC-MS/MS technique in a clinical setting
Therapeutic Advances in Endocrinology and MetabolismBackground: Saliva could be an attractive alternative to blood for assessing thyroid hormonal function. Objectives: Our goal was to determine if the levels of thyroid hormones in saliva can accurately reflect a person’s thyroid status and if they ...
Nadia Sawicka-Gutaj +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Environment International, 2018 Background: Few epidemiological studies have investigated associations of exposure to multiple metals with thyroid hormone homeostasis, especially for the pregnant women.
Jing Guo +9 more
doaj +1 more source
THE ACTION OF THYROID HORMONE [PDF]
Clinical Endocrinology, 1977 SUMMARYThyroid hormone affects both developmental and metabolic processes. It has a relatively specific effect on the synthesis of a number of enzymes and other proteins. The fundamental cellular mechanism of action seems to be at the level of genetic regulation.
J, Bernal, S, Refetoff
openaire +2 more sources