Results 31 to 40 of about 47,115 (244)

Etiopatogenia das tiroidites auto-imunes.

Acta Médica Portuguesa, 1989
The author reviews the etiopathogeny of autoimmune thyroiditis: sequestered antigen, clonal selection, acquired tolerance with low doses of antigen and disordered immunoregulation.
F M Carrilho
doaj   +1 more source

Leptin receptor antagonist attenuates experimental autoimmune thyroiditis in mice by regulating Treg/Th17 cell differentiation

Frontiers in Endocrinology, 2022
Leptin has been found to be involved in the development and progression of many autoimmune diseases. As an organ-specific autoimmune disease, the pathogenesis of Hashimoto’s thyroiditis has not been fully elucidated.
Wei Wang, Bo-Tao Zhang, Qi-Lan Jiang, Han-Qing Zhao, Qin Xu, Yang Zeng, Jia-Ying Xu, Jun Jiang   +7 more
doaj   +1 more source

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]

, 2015
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella, GIANFRILLI, DANIELE, GRANATO, SIMONA, LENZI, Andrea, PANIMOLLE, FRANCESCA, RADICIONI, Antonio, Semeraro, A, TIBERTI, Claudio   +7 more
core   +1 more source

Maternal Autoimmune Disease and Childhood-Onset Type 1 Diabetes: A Nationwide Population-Based Nested Case-Control Study. [PDF]

Pediatr Diabetes
Introduction Type 1 diabetes mellitus (T1DM) is an autoimmune disease that damages insulin‐producing pancreatic cells, often appearing in childhood. Global incidence is rising at 2%–3% yearly. Its exact cause is unclear. Prenatal exposures and maternal autoimmune disorders have been reported as potential risk factors.
Yen HC, Lin CH, Lin MC.
europepmc   +2 more sources

The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]

, 2008
Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Coexistence of Immune Checkpoint Inhibitor-Induced Autoimmune Diabetes and Pancreatitis

Frontiers in Endocrinology, 2021
Autoimmune diabetes is a rare but severe endocrine toxicity induced by immune checkpoint inhibitor (ICI) treatment. It is unclear if ICI causes selective islet toxicity or non-selective pancreas toxicity.
Amy L. Zhang, Fang Wang, Lee-Shing Chang, Marie E. McDonnell, Le Min   +4 more
doaj   +1 more source

Prevalence and clinical correlates of suicide attempts in patients with first-episode drug-naïve major depressive disorder and comorbid autoimmune thyroiditis

BJPsych Open
Background Autoimmune thyroiditis is closely associated with major depressive disorder (MDD) and suicide attempts. However, few studies have examined this relationship. Aims The study aimed to assess the prevalence and correlates of suicide attempts in
Yinli Luo, Yanan Zhou, Pu Peng, Ning Yuan, Xiangyang Zhang   +4 more
doaj   +1 more source

Thyroiditis and human blood metabolites: A mendelian randomization study [PDF]

Journal of Medical Biochemistry
Background: The risk factors for thyroiditis, an inflammatory disease with a complex etiology, remain poorly understood. Blood metabolites are known to change during thyroiditis development, suggesting a close relationship between blood metabolites and ...
Shao Lijie, Liu Siqi, Song Yongfu, Han Shaoyu, Ma Yue, Kunpeng Yang, Zhang Jingbin, Qi Bingxue, Guo Yan, Lu Xiaodan   +9 more
doaj   +1 more source

Sarcoidosis and Thyroid Autoimmunity [PDF]

Frontiers in Endocrinology, 2017
Most of the studies have shown a higher risk for subclinical and clinical hypothyroidism, antithyroid autoantibodies [overall antithyroid peroxidase antibodies (TPOAb)], and in general, thyroid autoimmunity, overall in the female gender in patients with sarcoidosis (S).
Fazzi P., Fallahi P., Ferrari S. M.
openaire   +4 more sources