Results 41 to 50 of about 231,563 (240)

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Hormonal and immunological features of autoimmune tyroiditis in persons in families with autoimmune diseases

Медицинская иммунология, 2020
Hormonal and immunological characteristics of have been studied in individuals with initial autoimmune thyroiditis who have first- and second-degree relatives with autoimmune diseases.
L. A. Bolotskaya, A. A. Tarlyun
doaj   +1 more source

Coexistence of Immune Checkpoint Inhibitor-Induced Autoimmune Diabetes and Pancreatitis

Frontiers in Endocrinology, 2021
Autoimmune diabetes is a rare but severe endocrine toxicity induced by immune checkpoint inhibitor (ICI) treatment. It is unclear if ICI causes selective islet toxicity or non-selective pancreas toxicity.
Amy L. Zhang, Fang Wang, Lee-Shing Chang, Marie E. McDonnell, Le Min   +4 more
doaj   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome [PDF]

, 1998
Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response.
G Steinhauser, M Hummel, D I Stott, C Berek, Hiepe, F., Berek, C., F Hiepe, Hummel, M., Steinhauser, G., Stott, D.I.   +9 more
core   +1 more source

The Impact of Environmental Factors on the Development of Autoimmune Thyroiditis—Review

Biomedicines
Autoimmune thyroiditis (Hashimoto’s thyroiditis) is the most common autoimmune disease. It most often manifests itself as hypothyroidism but may also present with euthyroidism or even hyperthyroidism.
Wojciech Cyna, Aleksandra Wojciechowska, Weronika Szybiak-Skora, Katarzyna Lacka   +3 more
doaj   +1 more source

Fine needle aspiration cytology of thyroid and its correlation with serological findings

Journal of Pathology of Nepal, 2017
Background: Thyroid autoimmunity can cause several forms of thyroid disorders i.e. Grave’s disease, Hashimoto’s thyroiditis, atrophic autoimmune thyroiditis, post-partum thyroidits etc. Cytological diagnosis may be sometimes difficult is some cases.
S Karki, A Shrestha
doaj   +1 more source

Preoperative Prediction of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma Using Arterial Enhancement Fraction Derived From Dual‐Layer Spectral CT

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of arterial enhancement fraction (AEF) derived from dual‐layer detector spectral CT (DLCT) in preoperative assessment of cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC), and to compare its performance with other spectral CT quantitative parameters and conventional CT ...
Lili Ye, Xiangfa He, Ming Liang, Yuxin Wei, Hao Zhang, Xiaomin Liu, Xiaolin Zheng   +6 more
wiley   +1 more source

The IL-4 Level among Patients with Autoimmune Thyroiditis in Al-Najaf Governorate, Iraq

Medical Journal of Babylon
Background: The study of autoimmune thyroiditis is considered one of the challenges of sustainable development. Autoimmune thyroiditis includes largely cellular and humoral immune responses targeted at the thyroid gland, including Graves thyroiditis and ...
Sarah Hasan Kadhum Al-Huchaimi, Mahdi Hussain Alammar, Sabah N. Al-Fatlawi   +2 more
doaj   +1 more source

Reactivity of anti-thyroid antibodies to thyroglobulin tryptic fragments: comparison of autoimmune and non-autoimmune thyroid diseases

Brazilian Journal of Medical and Biological Research, 1999
Studies concerning the antigenicity of thyroglobulin fragments allow the characterization of the epitopes but do not consider the role of heavier antigenic fragments that could result in vivo from the action of endoproteases.
L.H.B. Boechat, R.L. Zollner
doaj   +1 more source