Results 31 to 40 of about 231,563 (240)

T helper type 17 immune response plays an indispensable role for development of iodine-induced autoimmune thyroiditis in nonobese diabetic-H2h4 mice. [PDF]

open access: yes, 2009
T helper type 1(Th1)/Th2 paradigm has been expanded by discovery of a novel effector T cell (T(eff)) subset, Th17 cells, which produce a proinflammatory cytokine IL-17.
Eguchi, Katsumi   +7 more
core   +1 more source

Prevalence and clinical correlates of suicide attempts in patients with first-episode drug-naïve major depressive disorder and comorbid autoimmune thyroiditis

open access: yesBJPsych Open
Background Autoimmune thyroiditis is closely associated with major depressive disorder (MDD) and suicide attempts. However, few studies have examined this relationship. Aims The study aimed to assess the prevalence and correlates of suicide attempts in
Yinli Luo   +4 more
doaj   +1 more source

Thyroid autoimmunity and miscarriage [PDF]

open access: yesEuropean Journal of Endocrinology, 2004
To ascertain the strength of the association between thyroid autoimmunity and miscarriage, we performed a meta-analysis of both case-control and longitudinal studies performed since 1990 when this association was first described. A clear association between the presence of thyroid antibodies and miscarriage was found with an odds ratio (OR) of 2.73 (95
Mark F, Prummel, Wilmar M, Wiersinga
openaire   +2 more sources

Leptin receptor antagonist attenuates experimental autoimmune thyroiditis in mice by regulating Treg/Th17 cell differentiation

open access: yesFrontiers in Endocrinology, 2022
Leptin has been found to be involved in the development and progression of many autoimmune diseases. As an organ-specific autoimmune disease, the pathogenesis of Hashimoto’s thyroiditis has not been fully elucidated.
Wei Wang   +7 more
doaj   +1 more source

Cytokines in Thyroid Autoimmunity

open access: yesAutoimmunity, 2003
The role of cytokines in the pathogenesis of autoimmune thyroid disease (ATD) has been extensively investigated over the past years. In patients with ATD, these molecules can be found in both the thyroid and sites of extrathyroidal complications of the disease.
R A, Ajjan, A P, Weetman
openaire   +2 more sources

Thyroiditis and human blood metabolites: A mendelian randomization study [PDF]

open access: yesJournal of Medical Biochemistry
Background: The risk factors for thyroiditis, an inflammatory disease with a complex etiology, remain poorly understood. Blood metabolites are known to change during thyroiditis development, suggesting a close relationship between blood metabolites and ...
Shao Lijie   +9 more
doaj   +1 more source

Autoimmunity in thyroid disease

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2002
The autoimmune thyroid diseases, Graves' disease and autoimmune hypothyroidism, represent the two ends of a disease spectrum where an immune response is directed against the thyroid gland. In Graves' disease, antibodies directed against the thyrotropin receptor (TSH-R) lead to the development of glandular overactivity, while in autoimmune ...
Collins, J, Gough, S
openaire   +2 more sources

The Prevalence of Metabolic Syndrome in Patients with Euthyroid Autoimmune Thyroiditis

open access: yesCerrahpaşa Medical Journal, 2020
Objective: Autoimmune thyroid disease is one of the significant disorders of the thyroid gland and a common cause of primary hypothyroidism. Metabolic syndrome is an important metabolic disorder primarily associated with insulin resistance, diabetes ...
Ömer Arif Pamuk, Şakir Özgür Keşkek
doaj   +1 more source

Autoimmune Thyroid Disorders [PDF]

open access: yesJournal of Thyroid Research, 2011
Thyroid autoimmunity, as reflected by the presence in serum of autoantibodies directed against the thyroid autoantigens thyroglobulin (Tg) and thyroid peroxidase (TPO), is present in >10% of the US population over 12 years of age [1] and is the most common cause of endocrine dysfunction in iodine-sufficient populations [2].
Brown, Rosalind, Francis, Gary L.
openaire   +4 more sources

Influence of chondroitin 6-sulfate oligosaccharide unit addition on the immunopathogenicity of human thyroglobulin in cba/j(h-2k) mice. Multiple effects on antigen processing and t cell responses [PDF]

open access: yes, 2006
The site of type D (chondroitin 6-sulfate) oligosaccharide unit addition to human thyroglobulin (hTg) was localized. Furthermore, hTg and its fractions endowed with chondroitin 6-sulfate oligosaccaride units (hTg-CS) and devoid of it (hTg-CS-), were ...
Conte, Marisa
core   +1 more source

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