Results 141 to 150 of about 109,871 (361)
PD-L1 Inhibitor-Induced Thyroiditis is Associated with Better Overall Survival in Cancer Patients.
BACKGROUND Thyroid immune-related adverse events (IRAEs) have been reported more frequently with programmed cell death protein-1 (PD-1) inhibitors as compared to cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors, but there is limited data describing ...
A. Kotwal, L. Kottschade, Mabel Ryder
semanticscholar +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen+3 more
wiley +1 more source
Background: Amid the large panel of autoimmune thyroid diseases, Hashimoto’s thyroiditis (HT) represents a major point across multidisciplinary daily practice.
Ana Valea+9 more
doaj +1 more source
Existe controvérsia na literatura quanto à associação entre Carcinoma Papilífero de Tireoide (CPT) e Tireoidite de Hashimoto (TH) e também quanto a qual seria a relação etiológica entre ambos.
Luiz Alexandre Albuquerque Freixo Campos+4 more
doaj +1 more source
Thymus transplantation for complete DiGeorge syndrome: European experience [PDF]
Background: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods: Twelve patients with cDGS were transplanted with allogeneic cultured thymus.
Adrian J. Thrasher+59 more
core +2 more sources
EBV‐ MTX‐DLBCL shows higher driver gene mutation rates and worse outcomes after MTX discontinuation compared to EBV+ MTX‐DLBCL. IDD‐LPDs have lower mutation rates in genes related to clonal hematopoiesis (TET2/DNMT3A) and immune evasion (CD58) compared to EBV + DLBCL. ABSTRACT The WHO recently changed the outline of immunodeficiency/dysregulation (IDD)‐
Takumi Takahashi+12 more
wiley +1 more source
BackgroundImmune checkpoint inhibitors (ICPIs) have emerged as a powerful strategy to cancer treatment. However, while demonstrating antitumor efficacy, they can also induce a range of immune-related adverse events (irAEs).
Pengfei Zhao+4 more
doaj +1 more source
Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update. [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow.
Adorini+134 more
core +2 more sources
Mantle Cell Lymphoma of the Thyroid: A Rare Cause of Life‐Threatening Airway Compromise
The Kaohsiung Journal of Medical Sciences, EarlyView.
Kanokwan Kesornpatumanant+3 more
wiley +1 more source