Results 21 to 30 of about 1,081 (166)

Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function

open access: yesThe FEBS Journal, Volume 289, Issue 12, Page 3457-3476, June 2022., 2022
Mesenchyme homeobox protein 2 (MEOX2) is a transcription factor important for the development of bones and muscles. We report that MEOX2 is expressed in the nervous system, particularly localised to nociceptive dorsal root ganglia neurons, responsible for pain detection.
Tomislav Kokotović   +9 more
wiley   +1 more source

Normokalemic Thyrotoxic Periodic Paralysis with Acute Resolution in the Emergency Department

open access: yesClinical Practice and Cases in Emergency Medicine, 2017
Thyrotoxic periodic paralysis is a rare cause of acute paralysis in the emergency department (ED). The disorder is generally thought to be due to acute hypokalemia leading to paralysis.
James I. Gragg   +2 more
doaj   +1 more source

The long exercise test as a functional marker of periodic paralysis

open access: yesMuscle &Nerve, Volume 65, Issue 5, Page 581-585, May 2022., 2022
Abstract Aims The aim of this study was to evaluate the sensitivity of the long exercise test (LET) in the diagnosis of periodic paralysis (PP) and assess correlations with clinical phenotypes and genotypes. Methods From an unselected cohort of 335 patients who had an LET we analyzed 67 patients with genetic confirmation of PP and/or a positive LET ...
Ana Ribeiro   +7 more
wiley   +1 more source

A case report on thyrotoxic periodic paralysis from Dhaka, Bangladesh

open access: yesAdvances in Human Biology, 2020
Thyrotoxic periodic paralysis (TPP) is a disorder comprising acute hypokalaemia, intermittent muscle weakness and thyrotoxicosis. TPP is a rare manifestation of thyrotoxicosis predominantly seen in Asian people.
Nusrat Jahan, Afsana Begum, Mainul Haque
doaj   +1 more source

Mechanism of Thyrotoxic Periodic Paralysis [PDF]

open access: yesJournal of the American Society of Nephrology, 2012
The pathogenesis of thyrotoxic periodic paralysis has long been thought related to increased Na(+)-K(+) ATPase activity stimulated by thyroid hormone and/or hyperadrenergic activity and hyperinsulinemia. This mechanism alone, however, cannot adequately explain how hypokalemia occurs during acute attacks or the associated paradoxical depolarization of ...
Shih-Hua, Lin, Chou-Long, Huang
openaire   +2 more sources

Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 13, Issue 1, Page 355-367, February 2022., 2022
Abstract Background Thyroid hormone excess induces protein energy wasting, which in turn promotes muscle weakness and bone loss in patients with Graves' disease. Although most studies have confirmed a relationship between thyrotoxicosis and muscle dysfunction, few have measured changes in plasma metabolites and immune cells during the development and ...
Daiki Setoyama   +8 more
wiley   +1 more source

Thyrotoxic hypokalemic periodic paralysis [PDF]

open access: yesQJM, 2016
Learning points for clinicians Non-selective beta-blockers, avoidance of high-salt, carbohydrate-rich meals and strenuous exertion are essential in acute management, until thyrotoxicosis is treated. Unlike primary, or familial, hypokalemic periodic paralysis, potassium supplementation alone is ineffective.1 Acetazolamide and T4 supplementation may ...
A, Zayac   +5 more
openaire   +2 more sources

Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man

open access: yesCase Reports in Endocrinology, 2012
Thyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics.
Andrew Word   +2 more
doaj   +1 more source

Surgical treatment for thyrotoxic hypokalemic periodic paralysis: case report

open access: yesWorld Journal of Surgical Oncology, 2012
Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare, potentially life-threatening endocrine emergency. It is characterized by recurrent muscle weakness and hypokalemia.
Lin Yi-Chu   +7 more
doaj   +1 more source

Thyrotoxic Periodic Paralysis: Case Reports and an Up-to-Date Review of the Literature

open access: yesCase Reports in Endocrinology, 2011
Objectives. To describe 2 cases of thyrotoxic periodic paralysis. Methods. We report of 2 cases of thyrotoxic periodic paralysis in 2 individuals from 2 different backgrounds with emphasis on their presentation and treatment.
Abbi Lulsegged   +2 more
doaj   +1 more source

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