Results 31 to 40 of about 488,846 (185)
Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function
The FEBS Journal, Volume 289, Issue 12, Page 3457-3476, June 2022., 2022 Mesenchyme homeobox protein 2 (MEOX2) is a transcription factor important for the development of bones and muscles. We report that MEOX2 is expressed in the nervous system, particularly localised to nociceptive dorsal root ganglia neurons, responsible for pain detection.
Tomislav Kokotović +9 more
wiley +1 more source
The long exercise test as a functional marker of periodic paralysis
Muscle &Nerve, Volume 65, Issue 5, Page 581-585, May 2022., 2022 Abstract Aims The aim of this study was to evaluate the sensitivity of the long exercise test (LET) in the diagnosis of periodic paralysis (PP) and assess correlations with clinical phenotypes and genotypes. Methods From an unselected cohort of 335 patients who had an LET we analyzed 67 patients with genetic confirmation of PP and/or a positive LET ...
Ana Ribeiro +7 more
wiley +1 more source
A case report on thyrotoxic periodic paralysis from Dhaka, Bangladesh
Advances in Human Biology, 2020 Thyrotoxic periodic paralysis (TPP) is a disorder comprising acute hypokalaemia, intermittent muscle weakness and thyrotoxicosis. TPP is a rare manifestation of thyrotoxicosis predominantly seen in Asian people.
Nusrat Jahan, Afsana Begum, Mainul Haque
doaj +1 more source
Mechanism of Thyrotoxic Periodic Paralysis [PDF]
Journal of the American Society of Nephrology, 2012 The pathogenesis of thyrotoxic periodic paralysis has long been thought related to increased Na(+)-K(+) ATPase activity stimulated by thyroid hormone and/or hyperadrenergic activity and hyperinsulinemia. This mechanism alone, however, cannot adequately explain how hypokalemia occurs during acute attacks or the associated paradoxical depolarization of ...
Shih-Hua, Lin, Chou-Long, Huang
openaire +2 more sources
Journal of Cachexia, Sarcopenia and Muscle, Volume 13, Issue 1, Page 355-367, February 2022., 2022 Abstract Background Thyroid hormone excess induces protein energy wasting, which in turn promotes muscle weakness and bone loss in patients with Graves' disease. Although most studies have confirmed a relationship between thyrotoxicosis and muscle dysfunction, few have measured changes in plasma metabolites and immune cells during the development and ...
Daiki Setoyama +8 more
wiley +1 more source
Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
Case Reports in Endocrinology, 2012 Thyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics.
Andrew Word +2 more
doaj +1 more source
Surgical treatment for thyrotoxic hypokalemic periodic paralysis: case report
World Journal of Surgical Oncology, 2012 Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare, potentially life-threatening endocrine emergency. It is characterized by recurrent muscle weakness and hypokalemia.
Lin Yi-Chu +7 more
doaj +1 more source
Thyrotoxic periodic paralysis: an overview [PDF]
Annals of Saudi Medicine, 2004 Thyrotoxic periodic paralysis (TPP) is a fairly common manifestation of hyperthyroidism in Asian populations, with an incidence of about 1.9% in thyrotoxic patients, but it is rarely diagnosed among Caucasians and blacks in the Western world. The diagnosis often can be made on the basis of the clinical manifestations alone.
Hsieh, Chang-Hsun +9 more
openaire +2 more sources
Thyrotoxic hypokalemic periodic paralysis [PDF]
QJM, 2016 Learning points for clinicians Non-selective beta-blockers, avoidance of high-salt, carbohydrate-rich meals and strenuous exertion are essential in acute management, until thyrotoxicosis is treated. Unlike primary, or familial, hypokalemic periodic paralysis, potassium supplementation alone is ineffective.1 Acetazolamide and T4 supplementation may ...
A, Zayac +5 more
openaire +2 more sources
Thyrotoxic Periodic Paralysis: Correct Hypokalemia with Caution
Background: Thyrotoxic periodic paralysis is rare in Caucasian populations, but affects approximately 2% of East Asians with thyrotoxicosis (13% of males, 0.17% of females).
Cope TE, Samaraweera APR, Burn DJ
core +4 more sources