Results 211 to 220 of about 66,421 (262)

POSITIVE REGULATION OF HUMAN THYROTROPIN RECEPTOR mRNA BY THYROTROPIN

The Journal of Clinical Endocrinology & Metabolism, 1991
We have assessed the influence of natural and recombinant thyrotropin (TSH) on mRNA specific for the human TSH receptor (TSHR) in normal and abnormal adult human thyroid monolayer cells. Using physiological concentrations of TSH (less than 100 mU/L), a marked increase in the level of TSHR mRNA was observed within 12 hours and reached a greater than ...
G K, Huber, E S, Concepcion, P N, Graves, T F, Davies   +3 more
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Resistance to thyrotropin

Journal of Endocrinological Investigation, 2003
Resistance to TSH is a syndrome of reduced sensitivity to a biologically active TSH molecule. Subjects have elevated TSH levels but no goiter. However, thyroid hormone concentration may vary from normal to very high, depending on the severity of the resistance.
openaire   +2 more sources

Hypothalamic Thyrotropin-Releasing Hormone and Thyrotropin Biological Activity

Thyroid, 1998
Hypothalamic thyrotropin-releasing hormone (TRH) is the main positive regulator of thyrotropin (TSH) secretion. TRH action and the negative feedback of thyroid hormone are integrated in order to guarantee appropriate thyroid stimulation. TRH action affects various steps of the biosynthetic process within thyrotrophs, with major effects on the ...
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Binding of thyrotropin releasing hormone by thyrotropin-secreting cells

Biochemical and Biophysical Research Communications, 1973
Abstract In order to localize and identify receptor structures, the binding of radiolabeled thyrotropin releasing hormone (TRH) to thyrotropin (TSH)-secreting cells from rat and bovine anterior pituitaries and from a mouse TSH-secreting tumor was studied in vitro . The binding of TRH to rat anterior pituitaries increased linearly with the log of
Eddy, L J, Hershman, J M, Taylor, R E, Barker, S B   +3 more
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Thyrotropin Receptor

1990
This paper deals with the isolation, purification and functional characterization of the TSH receptor.
Akamizu T., DE LUCA, Michele, Kohn L. D.
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Effect of Thyrotropin-Releasing Hormone on Human Pituitary Thyrotropin, Prolactin, Placental Lactogen, and Chorionic Thyrotropin

The Journal of Clinical Endocrinology & Metabolism, 1973
The effect of synthetic thyrotropin releasing hormone (TRH) on serum thyrotropin (hTSH), prolactin (hPRL), chorionic thyrotropin (hCT), and placental lactogen (hPL) was investigated in 13 normal pregnant women who had therapeutic abortions at 8–22 weeks of gestation. Five hundred μg TRH injected iv increased serum hTSH consistently in all subjects. The
J M, Hershman, A, Kojima, H G, Friesen
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Thyrotropin Response to Thyrotropin Releasing Hormone in Normal Subjects

European Journal of Clinical Investigation, 1974
Abstract. 200 (ig of synthetic thyrotropin releasing hormone (TRH) was administered intravenously to six normal men and six normal women on two occasions. A positive correlation between the basal TSH level and maximal serum TSH after TRH was found. The TSH responses in the mid‐follicular and mid‐luteal phase were similar.
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[Thyrotropin].

Giornale di clinica medica, 1987
PLEBANI, MARIO, Gava R.
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Thyrotropin-releasing hormone and thyrotropin secretion.

The Journal of laboratory and clinical medicine, 1987
Thyrotropin (TSH) secretion is regulated primarily by thyroid hormones and thyrotropin-releasing hormone (TRH). Normally, TSH secretion is exquisitely sensitive to small increases and decreases in serum thyroid hormone concentrations when they occur as a result of alterations in thyroid secretion.
openaire   +1 more source

The Thyrotropin Receptor and Thyrotropin-Receptor Antibodies

Biochemical Society Transactions, 1979
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