Results 41 to 50 of about 66,698 (357)

Thyrotropin reference interval in older adults

Endocrine Connections
It is estimated that by the year 2050, 16% of the world’s population will be 65 years old and above. As the global aging population continues to grow, there is an increasing focus on thyroid disorders among older individuals.
Xiaodan Zhai, Yongze Li, Xiaochun Teng, Weiping Teng, Xiaoguang Shi, Zhongyan Shan   +5 more
doaj   +1 more source

Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]

, 2020
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter, Keller, Theresa, Kühnen, Peter, Minich, Waldemar B., Schomburg, Lutz, Schwiebert, Christian, Welsink, Tim, Wiegand, Susanna   +7 more
core   +1 more source

Evaluating the progression to abnormal thyrotropin in euthyroid preconception women: a population-based study

Thyroid Research
Background Abnormal preconception thyrotropin levels were associated with fecundability and adverse fetomaternal outcomes, however, little is known regarding the natural change of serum thyrotropin in euthyroid preconception women.
Rili Gao, Xinyi Lyu, Ying Yang, Jinrong Fu, Chuanyu Zhao, Haixia Guan, Xu Ma   +6 more
doaj   +1 more source

Study on the Interaction between Serum Thyrotropin and Semen Parameters in Men

Medical Sciences, 2022
The effect of thyroid function on semen parameters has been studied in pathological conditions in small studies. With this research work, we aimed to study thyroid hormone effects on semen parameters in 130 men who were evaluated for couple subfertility.
Ioannis Kakoulidis, Ioannis Ilias, Stefanos Stergiotis, Stefanos Togias, Aikaterini Michou, Anastasia Lekkou, Vasiliki Mastrodimou, Athina Pappa, Charalampos Milionis, Evangelia Venaki, Eftychia Koukkou   +10 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Associations of gestational thyrotropin levels with disease progression among pregnant women with differentiated thyroid cancer: a retrospective cohort study

Frontiers in Endocrinology
PurposePregnant women with a diagnosis of differentiated thyroid cancer (DTC) were potentially high-risk but largely ignored study population. We aimed to explore whether gestational thyrotropin levels were associated with progression of DTC.MethodsWe ...
Xin Li, Peng Fu, Wu-Cai Xiao, Fang Mei, Fan Zhang, Shanghang Zhang, Jing Chen, Rui Shan, Bang-Kai Sun, Shi-Bing Song, Chun-Hui Yuan, Zheng Liu   +11 more
doaj   +1 more source

Establishment of Reference Intervals for Thyroid-Associated Hormones Using refineR Algorithm in Chinese Population at High-Altitude Areas

Frontiers in Endocrinology, 2022
ObjectivesDiagnosis of thyroid disease among individuals dwelling at high altitude remains a challenge. Reference intervals (RIs) for thyroid-associated hormones among Tibetans living at various high altitudes were established to improve diagnosis ...
Chaochao Ma, Jian Zhong, Yutong Zou, Zhijuan Liu, Honglei Li, Jinrong Pang, Xiaoxing Liu, Zejipuchi, Liping Tian, Li’an Hou, Danchen Wang, Xinqi Cheng, Ling Qiu, Ling Qiu   +13 more
doaj   +1 more source

Thyrotropin Isoforms: Implications for Thyrotropin Analysis and Clinical Practice [PDF]

Thyroid, 2014
Serum thyrotropin (TSH) is considered the single most sensitive and specific measure of thyroid function in the general population owing to its negative logarithmic association with free triiodothyronine and free thyroxine concentrations. It is therefore often the test of choice for screening, diagnosis, and monitoring of primary hypothyroidism.
Joshua M, Estrada, Danielle, Soldin, Timothy M, Buckey, Kenneth D, Burman, Offie P, Soldin   +4 more
openaire   +2 more sources

Cell‐Stress‐Free Percutaneous Bioelectrodes

Advanced Materials, EarlyView.
A structurally adaptive soft microneedle bioelectrode is developed with an effervescent sacrificial core that dissolves after insertion, leaving an ultrathin and highly compliant electrode integrated with skin. This design enables ultra‐flexible, cell‐stress‐free, stable, and high‐fidelity electrophysiological monitoring under dynamic conditions such ...
Jungho Lee, Gaeun Yun, Juhyeong Jeon, Phuong Thao Le, Tae Sik Hwang, Jeongwoo Park, Jin‐Hyeok Baek, Seung Whan Kim, Hyoun Wook Lee, Kisang Kwon, Jihee Kim, Hoon Lim, Chulhong Kim, Sung‐Min Park, Geunbae Lim   +14 more
wiley   +1 more source