Results 31 to 40 of about 39,211 (211)

Autoantibody mimicry of hormone action at the thyrotropin receptor [PDF]

, 2022
Thyroid hormones are vital in metabolism, growth and development(1). Thyroid hormone synthesis is controlled by thyrotropin (TSH), which acts at the thyrotropin receptor (TSHR)(2).
Dror, Ron O., Carl-Mikael Suomivuori, Szkudlinski, Mariusz W, Billesbølle, Christian B, Pinto, Antonio FM, Suomivuori, Carl-Mikael, Kaihua Zhang, Billesbølle, Christian B., Faust, Bryan, Bryan Faust, Manglik, Aashish, Christian B. Billesbølle, Zhang, Kaihua, Singh, Isha, Hoppe, Nicholas, Yifan Cheng, Muftuoglu, Yagmur, Aashish Manglik, Diedrich, Jolene K., Saghatelian, Alan, Diedrich, Jolene K, Nicholas Hoppe, Yagmur Muftuoglu, Dror, Ron O, Cheng, Yifan, Mariusz W. Szkudlinski, Antonio F. M. Pinto, Ron O. Dror, Alan Saghatelian, Szkudlinski, Mariusz W., Jolene K. Diedrich, Pinto, Antonio F. M., Isha Singh   +32 more
core   +1 more source

Thyrotropin Isoforms: Implications for Thyrotropin Analysis and Clinical Practice [PDF]

Thyroid®, 2014
Serum thyrotropin (TSH) is considered the single most sensitive and specific measure of thyroid function in the general population owing to its negative logarithmic association with free triiodothyronine and free thyroxine concentrations. It is therefore often the test of choice for screening, diagnosis, and monitoring of primary hypothyroidism.
Joshua M, Estrada, Danielle, Soldin, Timothy M, Buckey, Kenneth D, Burman, Offie P, Soldin   +4 more
openaire   +2 more sources

Evaluating the progression to abnormal thyrotropin in euthyroid preconception women: a population-based study

Thyroid Research
Background Abnormal preconception thyrotropin levels were associated with fecundability and adverse fetomaternal outcomes, however, little is known regarding the natural change of serum thyrotropin in euthyroid preconception women.
Rili Gao, Xinyi Lyu, Ying Yang, Jinrong Fu, Chuanyu Zhao, Haixia Guan, Xu Ma   +6 more
doaj   +1 more source

Iodine deficiency is associated with increased thyroid hormone sensitivity in individuals with elevated TSH

European Thyroid Journal, 2023
Objective: Central sensitivity of thyroid hormone refers to the sensitivity of hypothalamic– pituitary–thyroid (HPT) axis to the change in circulating free thyroxine (fT4).
Ying Sun, Di Teng, Lei Zhao, Xiaoguang Shi, Yongze Li, Zhongyan Shan, Weiping Teng   +6 more
doaj   +1 more source

Hepatic hemangioendothelioma associated with production of humoral thyrotropin-like factor

, 2001
We report on 7 patients referred for treatment of hepatic hemangioendothelioma with increased thyrotropin levels. The serum thyroxine level was decreased in 4 and increased in 2.
Metcalfe, R, Davenport, M, Mark Davenport, Mieli-Vergani, G, Howard, E R, Russell Metcalfe, Ayling, R M, Charles R. Buchanan, Buchanan, C R, Hadzic, N, Giorgina Mieli-Vergani, Ruth M. Ayling, Nedim Hadzic, Edward R. Howard   +13 more
core   +1 more source

Effect of Delayed Elevation of Thyrotropin on Feeding Intolerance in Very Low Birth Weight Infants [PDF]

Neonatal Medicine, 2019
Purpose We investigated the effect of delayed elevation of thyrotropin (TSH) (deTSH) on gastrointestinal motility in very low birth weight infants (VLBWI).
Ju Kyung Hyun, So Yoon Choi, Yu Jin Jung, Jung Hyun Lee   +3 more
doaj   +1 more source

Interaction of the thyrotropin receptor on rat FRTL-5 thyroid cells with thyrotropin and a thyrotropin-stimulating autoantibody from Graves' patients

, 1987
FRTL-5 rat thyroid cells were either surface-labeled with 125I or biosynthetically labeled with [3H]N-acetylglucosamine, solubilized by lithium diiodosalicylate and immunoprecipitated after sequential exposure to bovine thyrotropin and anti-bovine ...
Chiovato L, Fenzi G, Pinchera A., Tombaccini D, Kohn LD, MACCHIA, ENRICO, ANTONELLI, ALESSANDRO, VITTI, PAOLO, Bartalena L   +8 more
core   +1 more source

Associations of gestational thyrotropin levels with disease progression among pregnant women with differentiated thyroid cancer: a retrospective cohort study

Frontiers in Endocrinology
PurposePregnant women with a diagnosis of differentiated thyroid cancer (DTC) were potentially high-risk but largely ignored study population. We aimed to explore whether gestational thyrotropin levels were associated with progression of DTC.MethodsWe ...
Xin Li, Peng Fu, Wu-Cai Xiao, Fang Mei, Fan Zhang, Shanghang Zhang, Jing Chen, Rui Shan, Bang-Kai Sun, Shi-Bing Song, Chun-Hui Yuan, Zheng Liu   +11 more
doaj   +1 more source

Structural changes caused by thyrotropin in thyroid cells and in liposomes containing reconstituted thyrotropin receptor.

, 1983
Thyrotropin causes a rapid and significant increase in the fluorescence polarization of DPH when this hydrophobic probe is incorporated into a strain of functioning rat thyroid cells (FRTL5).
Kohn L. D., ALOJ, SALVATORE MARIA, FORMISANO, SILVESTRO, Rotella C. M., BEGUINOT, FRANCESCO   +4 more
core   +1 more source

Ambient biothermal stress, preconceptional thyrotropin abnormalities, and the risk of preterm birth: a nationwide Chinese cohort study

Nature Communications
Epidemiologic evidence on thermal stress and preterm birth (PTB) is based on ambient temperature rather than a biothermal metric. Thyrotropin abnormalities have been associated with PTB and may increase thermal vulnerability.
Xinghou He, Mengyao Li, Hongbing Xu, Bin Zhang, Xinyi Lv, Long Wang, Chuanyu Zhao, Xuyang Shan, Yuan He, Yan Fang, Yuanyuan Wang, Huiying Xu, Jihong Xu, Xiaoming Song, Ya Zhang, Hongguang Zhang, Ying Yang, Xu Ma, Wei Huang   +18 more
doaj   +1 more source