Results 31 to 40 of about 33,764 (311)
Thyrotropin Isoforms: Implications for Thyrotropin Analysis and Clinical Practice [PDF]
Thyroid®, 2014 Serum thyrotropin (TSH) is considered the single most sensitive and specific measure of thyroid function in the general population owing to its negative logarithmic association with free triiodothyronine and free thyroxine concentrations. It is therefore often the test of choice for screening, diagnosis, and monitoring of primary hypothyroidism.
Joshua M, Estrada +4 more
openaire +2 more sources
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin
, 2013 There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
core +1 more source
The Two Faces of Janus: Why Thyrotropin as a Cardiovascular Risk Factor May Be an Ambiguous Target
Frontiers in Endocrinology, 2020 Elevated concentrations of free thyroid hormones are established cardiovascular risk factors, but the association of thyrotropin (TSH) levels to hard endpoints is less clear.
Johannes Wolfgang Dietrich +5 more
doaj +1 more source
Assessment of Thyrotropin-Releasing Hormone and Thyrotropin Reserve in Man [PDF]
Journal of Clinical Investigation, 1973 Endogenous thyrotropin-releasing hormone (TRH) reserve and pituitary thyrotropin (TSH) reserve were assessed in four normal subjects, three patients post-cryohypophysectomy, one patient with a hypothalamic lesion secondary to trauma, and four patients with Sheehan's syndrome. TSH reserve was determined by the immunoassayable TSH response to 500 mug TRH
P A, Singer, J T, Nicoloff
openaire +2 more sources
, 1990 Rat FRTL-5 and PC-Cl-3 thyroid cells are continuously cultured, clonal lines which require thyrotropin to grow and function. Both can be efficiently transformed when infected with RNA or DNA viruses carrying oncogenes or when directly transfected with ...
Grieco M. +8 more
core +2 more sources
Thyroid ResearchBackground Abnormal preconception thyrotropin levels were associated with fecundability and adverse fetomaternal outcomes, however, little is known regarding the natural change of serum thyrotropin in euthyroid preconception women.
Rili Gao +6 more
doaj +1 more source
European Thyroid Journal, 2023 Objective: Central sensitivity of thyroid hormone refers to the sensitivity of hypothalamic– pituitary–thyroid (HPT) axis to the change in circulating free thyroxine (fT4).
Ying Sun +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Effect of Delayed Elevation of Thyrotropin on Feeding Intolerance in Very Low Birth Weight Infants [PDF]
Neonatal Medicine, 2019 Purpose We investigated the effect of delayed elevation of thyrotropin (TSH) (deTSH) on gastrointestinal motility in very low birth weight infants (VLBWI).
Ju Kyung Hyun +3 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source