Results 41 to 50 of about 26,589 (251)

PET imaging of differentiated thyroid cancer with thyrotropin-alfa

Scientific Reports
Thyrotropin-alfa is an FDA approved recombinant human TSH agonist. This study represents a preclinical evaluation of thyrotropin-alfa as a thyroid-stimulating hormone receptor (TSHR)-targeted PET radiopharmaceutical, [89Zr]Zr-thyrotropin-alfa.
Grayson R. Gimblet, Pratheek Reddy, Michelle M. Holland, Hailey A. Houson, Jason Whitt, John A. Copland, Saad S. Kenderian, Renata Jaskula-Sztul, Suzanne E. Lapi   +8 more
doaj   +1 more source

The Difference in Thyroid Stimulating Hormone Levels between Differentiated Carcinoma and Benign Enlargement

International Archives of Otorhinolaryngology, 2020
Introduction Papillary and follicular thyroid carcinoma are common head and neck cancers. This cancer expresses a thyroid stimulating hormone (TSH) receptor that plays a role as a cancer stimulant substance.
Bambang Udji Djoko Rianto, Anton Sony Wibowo, Camelia Herdini   +2 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Fracture evolution of a thick soft protection layer and the water inrush mechanism in overburden under longwall mining

Deep Underground Science and Engineering, EarlyView.
Through shear–tensile creep tests and viscoelastic modeling, the fracture evolution of thick soft protective layers is clarified. Results show thickness‐dependent rheological failure modes that govern four types of roof water inrush, providing a mechanism‐based framework for hazard prediction and control. Abstract In the Jurassic coal‐bearing strata of
Mengnan Liu, Wei Qiao, Xianggang Cheng, Xiangsheng Meng, Peichao Feng   +4 more
wiley   +1 more source

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan, Diane Morfin, Marion Bernetiere, Marie Fauchet, Noël Peretti, Bérénice Segrestin, Pierre Poinsot   +6 more
wiley   +1 more source

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides

ESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot, Tarek Laouar, Antoine Beurnier, Nataliya Hrynchynshyn, Jean Christophe Eicher, Jean‐Michel Tartière, Patrick Jourdain, Olivier Lairez, Barnabas Gellen   +8 more
wiley   +1 more source

Significance of sampling time on thyroid-stimulating hormone, free thyroxine, and free triiodothyronine levels [PDF]

Journal of Medical Biochemistry
Background: The timing of sample collection is crucial for analytes with a circadian rhythm. Although blood samples are usually collected in the morning, they can also be collected in the afternoon.
Daglar Mahmut Mert, Orçun Asuman
doaj   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Reversal deterioration of renal function accompanied with primary hypothyrodism [PDF]

Vojnosanitetski Pregled, 2012
Introduction. Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance. These changes are usually overlooked in everyday practice.
Dragović Tamara
doaj   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source