Results 61 to 70 of about 1,533,467 (311)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Lattice Stability and Elastic Properties of Zr-Ti-X Alloys (X = Al, V) by the First Principles Study

Metals, 2020
Based on a certain ratio of Zr and Ti atomic fractions according to Zr47Ti45Al5V3 (wt.%), the lattice constants, lattice stability, and elastic properties of Zr-Ti-X alloys (X = Al, V) in body-centered cubic (BCC) (β phase) and hexagonal close-packed ...
Wenxiong Duan, Xiaoping Liang, Xiangguan Yang, Yu Wang, Baifeng Luan   +4 more
doaj   +1 more source

Microstructure and corrosion resistance of novel β-type titanium alloys manufactured by selective laser melting

Journal of Materials Research and Technology, 2022
Due to its unique characteristics selective laser melting offers the possibility to manufacture highly complex and functional parts out of otherwise difficult processable materials.
D. Pede, M. Li, L. Virovac, T. Poleske, F. Balle, C. Müller, H. Mozaffari-Jovein   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Development, exploration and optimization of porous titanium and titanium alloys: A review

Journal of Science: Advanced Materials and Devices
As an integrated material of structure and function, porous titanium (Ti) and Ti alloys with a porosity of (10–95%) processes a wide application prospect in many fields. However, they still faced some issues, including the design and optimization of pore
Baoguang Zhang, Kun Yang, Lei Shen, Xingyu Duan, Shaoyang Zhao, Wenbin Gao, Chenyang Xu, Jian Wang   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Properties of Mechanically Alloyed W-Ti Materials with Dual Phase Particle Dispersion

Metals, 2016
W alloys are currently widely studied materials for their potential application in future fusion reactors. In the presented study, we report on the preparation and properties of mechanically alloyed W-Ti powders compacted by pulsed electric current ...
František Lukáč, Monika Vilémová, Barbara Nevrlá, Jakub Klečka, Tomáš Chráska, Orsolya Molnárová   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Research status and development trend of high-strength β titanium alloys

Journal of Aeronautical Materials, 2020
β-Ti alloys have been used in many military/commercial aircraft since 1950s. Their high specific strength, good corrosion resistance, and high formability meet the special requirement of certain structures.
CHEN Wei, LIU Yunxi, LI Zhiqiang
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source