Results 51 to 60 of about 725,960 (242)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development, exploration and optimization of porous titanium and titanium alloys: A review

Journal of Science: Advanced Materials and Devices
As an integrated material of structure and function, porous titanium (Ti) and Ti alloys with a porosity of (10–95%) processes a wide application prospect in many fields. However, they still faced some issues, including the design and optimization of pore
Baoguang Zhang, Kun Yang, Lei Shen, Xingyu Duan, Shaoyang Zhao, Wenbin Gao, Chenyang Xu, Jian Wang   +7 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Lattice Stability and Elastic Properties of Zr-Ti-X Alloys (X = Al, V) by the First Principles Study

Metals, 2020
Based on a certain ratio of Zr and Ti atomic fractions according to Zr47Ti45Al5V3 (wt.%), the lattice constants, lattice stability, and elastic properties of Zr-Ti-X alloys (X = Al, V) in body-centered cubic (BCC) (β phase) and hexagonal close-packed ...
Wenxiong Duan, Xiaoping Liang, Xiangguan Yang, Yu Wang, Baifeng Luan   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Properties of Mechanically Alloyed W-Ti Materials with Dual Phase Particle Dispersion

Metals, 2016
W alloys are currently widely studied materials for their potential application in future fusion reactors. In the presented study, we report on the preparation and properties of mechanically alloyed W-Ti powders compacted by pulsed electric current ...
František Lukáč, Monika Vilémová, Barbara Nevrlá, Jakub Klečka, Tomáš Chráska, Orsolya Molnárová   +5 more
doaj   +1 more source

Electrochemical Noise Analysis of the Corrosion of Titanium Alloys in NaCl and H₂SO₄ Solutions

Metals, 2021
Titanium alloys have been used in aerospace, aeronautic, automotive, biomedical, structural, and other applications because titanium alloys have less density than materials like steel and support higher stress than Al-alloys.
Jesús Manuel Jáquez-Muñoz, Citlalli Gaona-Tiburcio, Jose Cabral-Miramontes, Demetrio Nieves-Mendoza, Erick Maldonado-Bandala, Javier Olguín-Coca, Luis Daimir López-Léon, Juan Pablo Flores-De los Rios, Facundo Almeraya-Calderón   +8 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effects of powder conditioning on the quality, microstructure and mechanical properties of sintered titanium alloys [PDF]

, 2015
A small amount of internal lubricant (Stearic acid (SA) or Magnesium stearate (MgSt)) was added to Ti powder for the purpose of improving the compressibility and the green density homogeneity.
Lou, Jia
core