Results 61 to 70 of about 766,214 (296)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Ti–15Zr and Ti–15Zr–5Mo Biomaterials Alloys: An Analysis of Corrosion and Tribocorrosion Behavior in Phosphate-Buffered Saline Solution

, 2023
It is crucial for clinical needs to develop novel titanium alloys feasible for long-term use as orthopedic and dental prostheses to prevent adverse implications and further expensive procedures. The primary purpose of this research was to investigate the
Teixeira, Jean Valdir Uchôa [UNESP], Adriana Alencar Santos, Correa, Diego Rafael Nespeque [UNESP], Carlos Alberto Fonzar Pintão, Diego Rafael Nespeque Correa, Pintão, Carlos Alberto Fonzar [UNESP], Grandini, Carlos Roberto [UNESP], Carlos Roberto Grandini, Santos, Adriana Alencar [UNESP], Jean Valdir Uchôa Teixeira, Paulo Noronha Lisboa-Filho, Lisboa-Filho, Paulo Noronha [UNESP], Grandini, Carlos Roberto, Correa, Diego Rafael Nespeque, Santos, Adriana Alencar, Pintão, Carlos Alberto Fonzar, Lisboa-Filho, Paulo Noronha, Teixeira, Jean Valdir Uchôa   +17 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Low temperature heat treatments on Ti-15Zr-xMo alloys

, 2017
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Processo FAPESP: #2010/20440-7CNPq: #307.279/2013-8CNPq: #481313/2012-5CNPq: #490761/2013-5This paper regards the study of ...
Rocha, Luís Augusto, Caio Castanho Xavier, Correa, Diego Rafael Nespeque [UNESP], Luís Augusto Rocha, Xavier, Caio Castanho, Rocha, Luís Augusto [UNESP], Diego Rafael Nespeque Correa, Grandini, Carlos Roberto, Correa, Diego Rafael Nespeque, Grandini, Carlos Roberto [UNESP], Carlos Roberto Grandini, Xavier, Caio Castanho [UNESP]   +11 more
core   +1 more source

Tailorable copper-bearing titanium alloys with remarkable strength and ductility fabricated by spark plasma sintering for biomedical applications

Journal of Materials Research and Technology
Titanium and Ti-based alloys are widely used metallic biomaterials, however, the surgical infections related to bacteria always occur on the implants. Developing the antibacterial titanium alloys has been studied as one of the most effective methods to ...
Zhanfei Wang, Yaoxin Huo, Ying Qin, Ruipeng Guo, Jinling Zhang, Changjiang Zhang, Min Cheng, Lifeng Zhang, Chao Cai, Yusheng Shi   +9 more
doaj   +1 more source

Effect of α+β solution treatment and aging on the performance of powder forged Ti-5Al-2.5Fe

Heat Treatment and Surface Engineering, 2023
Amongst titanium alloys, the α+β Ti alloys are the ones with the best compromise between strength and fracture toughness. However, the applicability of α+β Ti alloys is limited by their higher cost compared to other structural metals.
L. Bolzoni, F. Yang, M. Jia
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source